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Full Description
Gene-Environment Interactions in Birth Defects and Developmental Disorders, Volume 152, covers the multifactorial etiology of a variety of developmental disorders, including orofacial clefts, fetal alcohol spectrum disorders, autism, and others. The causes of individual cases of most common birth defects are unknown but likely involve a combination of genetic predisposition and environmental exposures. How these risk factors interact in the genesis of these conditions is still largely unknown and readers will find the latest information and ideas on these disorders, along with discussion of the challenges and opportunities for furthering knowledge in this area.
Contents
Gene-environment interactions in birth defect etiology: Challenges and opportunities
Robert J. Lipinski and Robert S. Krauss
Transgenerational inheritance and its modulation by environmental cues
Roxane Verdikt, Abigail A. Armstrong, and Patrick Allard
Gene-alcohol interactions in birth defects
Joshua L. Everson and Johann K. Eberhart
The role of genes and environment in the etiology of congenital diaphragmatic hernias
Nathan G. Burns and Gabrielle Kardon
Gene-environment interactions in the pathogenesis of common craniofacial anomalies
Sharien Fitriasari and Paul A. Trainor
Genexenvironment associations in orofacial clefting
Mary L. Marazita
Gene-environment interactions underlying the etiology of neural tube defects
Carlo Donato Caiaffa, Cristiane Sá Roriz Fonteles, Lei Yunping, and Richard H. Finnell
Genexenvironment interactions in autism spectrum disorders
Kimberly Keil-Stietz and Pamela J. Lein