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Full Description
Oxidative Stress and Dietary Antioxidants in Neurological Diseases provides an overview of oxidative stress in neurological diseases and associated conditions, including behavioral aspects and the potentially therapeutic usage of natural antioxidants in the diet. The processes within the science of oxidative stress are described in concert with other processes, such as apoptosis, cell signaling, and receptor mediated responses. This approach recognizes that diseases are often multifactorial and oxidative stress is a single component of this. The book examines basic processes of oxidative stress—from molecular biology to whole organs—relative to cellular defense systems, and across a range of neurological diseases.
Sections discuss antioxidants in foods, including plants and components of the diet, examining the underlying mechanisms associated with therapeutic potential and clinical applications. Although some of this material is exploratory or preclinical, it can provide the framework for further in-depth analysis or studies via well-designed clinical trials or the analysis of pathways, mechanisms, and components in order to devise new therapeutic strategies. Very often oxidative stress is a feature of neurological disease and associated conditions which either centers on or around molecular and cellular processes. Oxidative stress can also arise due to nutritional imbalance during a spectrum of timeframes before the onset of disease or during its development.
Contents
ForewordUna Macleod
Part I: Oxidative stress and neurological diseases
1. The role of reactive oxygen species in the pathogenic pathways of depressionMasakazu Ibi and Chihiro Yabe-Nishimura
2. The relationship between the blood-brain barrier, degenerative neuropathy, and oxidative stressDavid Fisher and Olufemi A. Alamu
3. Neuroinflammatory processes and oxidative stressTameka A. Clemons, Na'Taki Osborne Jelks, L. Monique Vance, and Kimberly Williams
4. Revisiting the oxidative stress theory of aging: Molecular mechanisms underlying brain agingJoana C. d'Avila
5. Neuroblastoma and oxidative stress: From pathogenesis to in vitro models of neurodegenerationAnthea Di Rita and Flavie Strappazzon
6. Oxidative stress in epileptogenesis: Febrile seizures, chemoconvulsant pilocarpine, and electrical stimulationDavid Agustin León Navarro, María Crespo, and Mairena Martín
7. DJ-1 in astrocytic neuroprotection to oxidative stressAmanda J. Edson, Helena A. Hushagen, and Kari E. Fladmark
8. Oxidative stress markers in seizures and epilepsy: Methods and applications to modelsLaura Medina-Ceja, Kenia Pardo-Peña, and Alberto Morales-Villagrán
Part II: Antioxidants and neurological diseases
9. Antioxidant therapy, oxidative stress, and blood-brain barrier: The road of dietary antioxidantsMiguel Pinto, Sofia Benfeito, Carlos Fernandes, and Fernanda Borges
10. Antioxidant and neuroprotective properties of Mediterranean oils: Argan oil, olive oil, and milk thistle seed oilAsmaa Badreddine, Amira Zarrouk, Wiem Meddeb, Thomas Nury, Leila Rezig, Meryam Debbabi, Fatima Zohra Bessam, Fatiha Brahmi, Anne Vejux, Mondher Mejri, Boubker Nasser, and Gérard Lizard
11. Aromatic plants: A source of compounds with antioxidant and neuroprotective effectsSandra Gonc¸alves, Inês Mansinhos, and Anabela Romano
12. The elderly, use of antioxidants and memoryWilliam K. Summers
13. Aspidosperma pyrifolium Mart. antioxidants features and neuronal tissuesDayane Pessoa de Araújo and Glauce Socorro de Barros Viana
14. Berberine neuroprotection and antioxidant activityMohsen Imenshahidi and Hossein Hosseinzadeh
15. Carnosic acid and carnosol: Neuroprotection and the mitochondriaMarcos Roberto de Oliveira
16. Coconut oil and antioxidative neuroprotectionSiong Meng Lim, Nur Syafiqah Rahim, and Kalavathy Ramasamy
17. Antioxidant effects of Curcuma longa and its active constituent, curcumin, for the therapy of neurological disordersBibi Marjan Razavi and Hossein Hosseinzadeh
18. Neuroprotective mechanisms of Ginkgo biloba against oxidative stressHoi Man Cheung and David Tai Wai Yew
19. Morinda citrifolia Linn. (Noni) fruit, antioxidant effects, and neuroprotectionVijayapandi Pandy, Srinivasa Reddy Bonam, Anji Reddy Raya, and Rama Rao Nadendla
20. Naringin and naringenin in neuroprotection and oxidative stressPauline Maciel August and Bernardo Gindri dos Santos
21. Nigella sativa L. and thymoquinone as neuroprotective antioxidantsAlireza Tavakkoli and Hossein Hosseinzadeh
22. Dietary antioxidants, epigenetics, and brain aging: A focus on resveratrolChristian Griñán-Ferré, Vanesa Izquierdo, and Mercè Pallàs
23. The role of saffron and its main components on oxidative stress in neurological diseases: A reviewMarjan Nassiri-Asl and Hossein Hosseinzadeh
24. Sulforaphane and its modulation of brain redox status: The mitochondria as a targetMarcos Roberto de Oliveira
25. Recommended resources for oxidative stress and dietary antioxidants in neurological diseasesRajkumar Rajendram, Vinood B. Patel, and Victor R. Preedy
Index
