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Full Description
The Choroid Plexus and Cerebrospinal Fluid: Emerging Roles in CNS Development, Maintenance, and Disease Progression combines new and established work to allow for cross-disciplinary discussion and showcase newfound excitement surrounding the choroid plexus and cerebrospinal fluid (CSF). This book is of great utility to neuroscientists interested in biological questions about cancer, multiple sclerosis, Alzheimer's, choroid plexus, or CSF research, and especially for researchers looking to expand their research into later stages of their disease of interest, such as metastasis. No other resource is currently available which addresses these issues in this fashion. The focus on the choroid plexus provides a practical resource on modeling clinical issues influenced by this brain region for researchers from students to principal investigators.
Contents
1. Introduction to the Ventricular System and Choroid Plexus
Tatsuhiro Fujii, Joshua Youssefzadeh, Michael Novel and Josh Neman
2. Development of brain ventricles and choroid plexus
Ellen M. Carpenter
3. Choroid plexus: Structure and Function
Florence M. Hofman and Thomas C. Chen
4. Towards an artificial choroid plexus, concept and clinical implications
Thomas Brinker and John Morrison
5. Choroid Plexus Tumors
Sean A. Grimm and Marc C. Chamberlain
6. Role of Blood Brain Barrier, Choroid Plexus, and Cerebral Spinal Fluid in Extravasation and Colonization of Brain Metastases
Cecilia Choy and Josh Neman
7. The Role of the Choroid Plexus in the Pathogenesis of Multiple Sclerosis
Vahan Martirosian, Alex Julian and Josh Neman
8. The Choroid Plexus and Cerebrospinal Fluid system: roles in neurodegenerative diseases
Jérôme Badaut and Jean-François Ghersi-Egea
9. Delivery Considerations for Targeting the Choroid Plexus-Cerebrospinal Fluid Route
Thomas C. Chen
Glossary
