Full Description
An understanding of the nervous system at virtually any level of analysis requires an understanding of its basic building block, the neuron. The third edition of From Molecules to Networks provides the solid foundation of the morphological, biochemical, and biophysical properties of nerve cells. In keeping with previous editions, the unique content focus on cellular and molecular neurobiology and related computational neuroscience is maintained and enhanced.
All chapters have been thoroughly revised for this third edition to reflect the significant advances of the past five years. The new edition expands on the network aspects of cellular neurobiology by adding new coverage of specific research methods (e.g., patch-clamp electrophysiology, including applications for ion channel function and transmitter release; ligand binding; structural methods such as x-ray crystallography).
Written and edited by leading experts in the field, the third edition completely and comprehensively updates all chapters of this unique textbook and insures that all references to primary research represent the latest results.
Contents
SECTION I. CELLULAR AND MOLECULAR
1. Cellular Components of Nervous Tissue - Patrick R. Hof, Graham Kidd, Javier DeFelipe, Jean de Vellis, Miguel A. Gama Sosa, Gregory A. Elder and Bruce D. Trapp
2. Subcellular Organization of the Nervous System: Organelles and Their Functions - Scott Brady and Peter Brophy 3. Energy Metabolism in the Brain - Gerald Dienel
4. Intracellular Signaling - Howard Schulman
5. Regulation of Neuronal Gene Expression and Protein Synthesis - Cristina Alberini and Eric Klann
6. Modeling and Analysis of Intracellular Signaling Pathways - Paul D. Smolen, Douglas A. Baxter and John H. Byrne
7. Pharmacology and Biochemistry of Synaptic Transmission: Classical Transmitters - Ariel Y. Deutch and Robert H. Roth
8. Nonclassic Signaling in the Brain - Ariel Y. Deutch, Andrea Giuffrida and James L. Roberts
9. Connexin- and Pannexin-Based Channels in the Nervous System: Gap Junctions and More - Juan C. Sáez and Bruce Nicholson
10. Neurotransmitter Receptors - M. Neal Waxham
11. Molecular Properties of Ion Channels - Jason Tien, Yuh Nung Jan and Lily Yeh Jan
SECTION II. PHYSIOLOGY OF ION CHANNELS, EXCITABLE MEMBRANES AND SYNAPTIC TRANSMISSION
12. Membrane Potential and Action Potential - David A. McCormick
13. Biophysics of Voltage-Gated Ion Channels - Diane Lipscombe
14. Dynamical Properties of Excitable Membranes - Douglas A. Baxter and John H. Byrne
15. Release of Neurotransmitters - Robert S. Zucker, Dimitri M. Kullmann and Pascal S. Kaeser
16. Postsynaptic Potentials and Synaptic Integration - John H. Byrne
17. Cable Properties and Information Processing in Dendrites - Michael Beierlein
SECTION III. INTEGRATION
18. Synaptic Plasticity - Ruth Heidelberger, Harel Shouval, Robert S. Zucker and John H. Byrne
19. Information Processing in Neural Networks - James J. Knierim
20. Learning and Memory: Basic Mechanisms - John H. Byrne, Kevin S. LeBar, Joseph LeDoux, Glenn E. Schafe and Richard F. Thompson
21. Molecular Mechanisms of Neurological Disease - Monica Gireud, Natalie Sirisaengtaksin and Andrew J. Bean
