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基本説明
Include articles from "Handbook of Cell Signaling, 2nd edition", and new contents.
Full Description
Cytosol, the liquid found inside cells, is the site for multiple cell processes, including signaling from the cell membrane to sites within the cell. Cytosolic signaling mechanisms are researched and studied in graduate programs in cell biology, molecular biology, biochemistry, pharmacology, molecular and cellular physiology, pharmacy, and biomedical sciences.
Contents
Volume two includes 183 chapters divided in 8 sections, including:
Section A: Protein Phosphorylation
56 Eukaryotic Kinomes: Genomics and Evolution of Protein Kinases
57 Modular Protein Interaction Domains in Cellular Communication
58 Structures of Serine/Threonine and Tyrosine Kinases
59 Protein Tyrosine Kinase Receptor Signaling Overview
60 Signaling by the Platelet-Derived Growth Factor Receptor Family
61 The Epidermal Growth Factor Receptor Family
62 Mechanisms and Functions of Eph Receptor Signaling
63 Cytokine Receptor Signaling
64 The Negative Regulation of JAK/STAT signaling
65 Protein Kinase Inhibitors
66 Integrin Signaling: Cell Migration, Proliferation, and Survival
67 Downstream Signaling Pathways: Modular Interactions
68 Non-Receptor Tyrosine Kinases in T Cell Antigen Receptor Function
69 Receptor Tyrosine Kinase Signaling and Ubiquitination
70 TGFb Signal Transduction
71 Mitogen-Activated Protein Kinases
72 Recognition of Phospho-Serine/Threonine Phosphorylated Proteins
73 AMP-Activated Protein Kinase
74 Principles of Kinase Regulation
75 Calcium/Calmodulin-Dependent Protein Kinase II
76 Glycogen Synthase Kinase 3
77 The PIKK Family of Protein Kinases
78 Histidine Kinases in Two-Component Signaling Pathways
79 The EF2K/MHCK/TRPM7 Family of Atypical Protein Kinases
80 The Leucine-Rich Repeat Receptor Protein Kinases of Arabidopsis thaliana
81 Engineering Protein Kinases with Specificity for Unnatural Nucleotides and Inhibitors
82 Clinical Applications of Kinase Inhibitors in Solid Tumors
83 Ubiquitin-Mediated Regulation of Protein Kinases in NFκB Signaling
84 Global Analysis of Phosphoregulatory Networks
Section B: Protein Dephosphorylation
85 Phosphatase Families Dephosphorylating Serine and Threonine Residues in Proteins
86 The Structure and Topology of Protein Serine/Threonine Phosphatases
87 Naturally Occurring Inhibitors of Protein Serine/Threonine Phosphatases
88 Protein Phosphatase 1 Binding Proteins
89 Protein Serine/Threonine Phosphatase Inhibitors and Human Disease
90 Calcineurin
91 Protein Serine/Threonine-Phosphatase 2C (PP2C)
92 Approaches to the Identification of Protein Tyrosine Phosphatase Substrates
93 Inhibitors of Protein Tyrosine Phosphatases
94 Regulating Receptor PTP Activity
95 CD45
