基本説明
Aims to inform biomedical researchers about recent applications of modern data analysis and simulation methods as applied to biomedical research.
Full Description
The combination of faster, more advanced computers and more quantitatively oriented biomedical researchers has recently yielded new and more precise methods for the analysis of biomedical data. These better analyses have enhanced the conclusions that can be drawn from biomedical data, and they have changed the way that experiments are designed and performed. This volume, along with the 2 previous Computer Methods volumes for the Methods in Enzymology serial, aims to inform biomedical researchers about recent applications of modern data analysis and simulation methods as applied to biomedical research.
Contents
Predicting Fluorescence Lifetimes and Spectra of Biopolymers
Patrik R. Callis
Modeling of Regulatory Networks: Theory and Applications in the study of the Drosophila Circadian Clock
Elizabeth Y. Scribner, Hassan M. Fathallah-Shaykh
Strategies for articulated multibody-based adaptive coarse grain simulation of RNA
Mohammad Poursina, Kishor D. Bhalerao, Samuel C. Flores , Kurt S. Anderson, Alain Laederach
Modeling Loop Entropy
Gregory S. Chirikjian
Inferring Functional Relationships and Causal Network Structure from Gene Expression Profiles
Radhakrishnan Nagarajan
Numerical solution of the chemical master equation: uniqueness and stability of the stationary distribution for chemical networks, and mRNA bursting in a gene network with negative feedback regulation
E. S. Zeron, M. Santill_an
How molecular should your molecular model be? On the level of molecular detail required to simulate biological networks in systems and synthetic biology
Didier Gonze, Wassim Abou-Jaoud'e, Adama Ouattara, and Jos'e Halloy
Computational modelling of biological pathways by executable biology
Maria Luisa Guerriero John K. Heath
Computing Molecular Fluctuations in Biochemical Reaction Systems Based on A Mechanistic, Statisitical Theory of Irreversible Processes
Don Kulasiri
Probing the input-output behaviour of biochemical and genetic systems: system identification methods from control theory
David McMillen, Brian Ingalls, Jordan Ang
Biochemical pathway modelling tools for drug target detection in cancer and other complex diseases
Alberto Marin-Sanguino, Shailendra K. Gupta, Eberhard O. Voit and Julio Vera
Deterministic and Stochastic Simulation and Analysis of Biochemical Reaction Networks: The Lactose Operon Example
Necmettin Yildirim, Caner Kazanci F
Multivariate Neighborhood Sample Entropy: A method for data reduction and prediction of complex data.
Joshua S. Richman MD, PhD
Scaling differences of heartbeat excursions between wake and sleep periods
L. Guzm'an-Vargas, I. Reyes-Ram'ırez, R. Hern'andez-P'erez, F. Angulo-Brown
Changepoint analysis for single-molecule polarized totalinternal reflection fluorescence microscopy experiments
John F. Beausang, Yale E. Goldman, and Philip C. Nelson
Inferring mechanisms from dose-response curves
Carson C. Chow, Karen M. Ong, Edward J. Dougherty, and S. Stoney Simons, Jr.
Spatial Aspects in Biological System Simulations
Haluk Resat, Michelle N. Costa, and Harish Shankaran
Computational Approaches to Modeling Viral Structure and Assembly
Stephen C. Harvey, Anton S. Petrov, Batsal Devkota and Mustafa Burak Boz
An Object-Oriented Software Suite for the Simulation and Design of Macromolecules
Andrew Leaver-Fay, Michael Tyka, Steven M. Lewis, Oliver F. Lange, James Thompson, Ron Jacak, Kristian Kaufman, P. Douglas Renfrew, Colin A. Smith, Will Sheffler, Ian W. Davis, Seth Cooper, Adrien Treuille, Daniel J. Mandell, Florian Richter, Yih-En Andrew Ban, Sarel J. Fleishman, Jacob E. Corn, David E. Kim, Sergey Lyskov, Monica Berrondo, Stuart Mentzer, Zoran Popović, James J. Havranek, John Karanicolas, Rhiju Das, Jens Meiler, Tanja Kortemme, Jeffrey J. Gray, Brian Kuhlman1, David Baker, and Philip Bradley
Computational Design of Intermolecular Stability and Specificity in Protein Self-Assembly
Vikas Nanda, Sohail Zahid, Fei Xu, Daniel Levine
