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基本説明
A one-stop resource for referencing zebrafish research that integrates and synthesizes all aspects of zebrafish biology in one location.
Full Description
This cutting-edge resource includes up-to-date information on zebrafish physiology and the tools used to study it, not only as a model species for studies of other vertebrates but with application for studies of human disease and aquatic toxicology. The utility of zebrafish for physiological research is based on several key features including i) a "fully" sequenced genome, ii) rapid (‾3 month) generation times), iii) their capacity to produce large numbers of externally fertilized eggs, iv) optical transparency of embryos and larvae, and v) the applicability of reverse and forward genetics to assess gene function. Gene knockdown in embryos and the production of transgenic strains are now standard techniques being used to assess physiology. This book will be of keen interest not only to the typical readers of Fish Physiology but also to biomedical researchers, toxicologists and developmental biologists.
Contents
Genetic Tools
Organisation and Physiology of the Zebrafish Nervous System
Zebrafish Vision; The Zebrafish Inner Ear
Endocrinology of Zebrafish
Developmental Physiology of the Zebrafish Cardiovascular System
Respiration
Ionic and Acid-Base Regulation
The Zebrafish as a Model for Human Disease
Perspectives on Zebrafish as a Model in Environmental Toxicology