基本説明
The definitive translational reference in the field of nephro-endocrinology, investigating both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems.
Full Description
The Textbook of Nephro-Endocrinology is the definitive translational reference in the field of nephro-endocrinology, investigating both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems. It offers researchers and clinicians expert, gold-standard analyses of nephro-endocrine research and translation into the treatment of diseases such as anemia, chronic kidney disease (CKD), rickets, osteoporosis, and, hypoparathyroidism.
Contents
Part 1: The Kidney as an Endocrine Organ
Section 1: Erythropoietin
1. Erythropoientin: An Historical Overview of Physiology, Molecular Biology And Gene Regulation
2.Erythropoiesis: The Role of Erythropoietin and Iron
3.Extra-Hematopoietic Action of Erythropoietin
4.Development of Recombinant Erythropoietin and Erythropoietin Analogues
5.Erythropoietin Disease States & Resistance
Section 2: Vitamin D, PTH and Novel Regulators of Phosphate
6. Vitamin D and the Kidney: Introduction and Historical Perspective
7.Vitamin D: Molecular Biology and Gene Regulation
8.Molecular Biology of Parathyroid Hormone
9.Endocrine Regulation of Phosphate Homeostasis
Section 3: Renin-angiotensin
10.Introduction and Historical Overview
11.Molecular Biology of Renin and Regulation of Its Gene
12. Physiology and Regulation of the RAAS System
13. The Renin Angiotensin Aldosterone System and the Kidney
14. The Renin Angiotensin and the Heart
15. The Renin-Angrotensin blockade: Therapeutic Agents
Part 2: The Kidney as a Hormonal target
Section 4: Anti-diuretic Hormone
16. Vasopressin in the Kidney: Historical Aspects
17. Molecular Biology and Gene Regulation
18. Vasopressin Antagonists in Physiology and Disease
19. Diabetes Insipidus and SIADH
Section 5: The Atrial Natriuretic Peptides
20. ANP, BNP and CNP Physiology and Pharmacology of the Cardiorenal Axis
Section 6: Aldosterone
21.Introduction and Historical Overview
22.Aldosterone Receptors and Their Renal Effects: Molecular Biology and Gene Regulation
23. Aldosterone and Its Cardiovascular Effects
24. Aldosterone Regulation
Section 7: Endocrine Disorders in Renal Failure
25. Insulin resistance
26. Growth hormone
27. Sexual Dysfunction in Men and Women with Chronic Kidney Disease
28. Thyroid Status in Chronic Renal Failure Patients
29.Metabolic Acidosis of Chronic Kidney Disease
30.Pregnancy and the Kidney