基本説明
加齢に関する動物モデルを結集したハンドブック。各動物モデルごとに、生物学、栄養学、寿命に関する要因、年齢推測法、実験利用、また加齢に関わる疾患を網羅。
Contents: I. Introduction- II. Animal Models- C. Elegans; Drosophila; Zebrafish; Rat, Mouse; Non-human primate; Senesence accelerated animals; Knock out models; Cell culture; Apoptosis; III. Comparative Models of Aging and Age-Related Diseaes; Alzheimer's; Parkinson's; Depression; Osteoporosis; Joint disease; and more.
Full Description
The Handbook of Models for Human Aging is designed as the only comprehensive work available that covers the diversity of aging models currently available. For each animal model, it presents key aspects of biology, nutrition, factors affecting life span, methods of age determination, use in research, and disadvantages/advantes of use. Chapters on comparative models take a broad sweep of age-related diseases, from Alzheimer's to joint disease, cataracts, cancer, and obesity. In addition, there is an historical overview and discussion of model availability, key methods, and ethical issues.
Contents
I. IntroductionII. Animal ModelsIII. Comparative Models of Aging and Age-Related Diseases
