Brandon/Hill Medical List minimal-core, first-purchase selection (#516). Resource on pharmacologic drug therapeutics emphasizes the basic principles and includes new information on drug transporters, pharmacokinetics, and drug metabolism. Previous ed.: 2005.
The landmark text in medical pharmacology is now in full colorIncludes DVD with image bankA Doody's Core Title for 2017!4 STAR DOODY'S REVIEW!"This 12th edition of the most authoritative book in pharmacology is the best both in content and physical appearance....This edition of Goodman & Gilman's continues to be the most authoritative and widely used resource bridging the discipline of pharmacology with therapeutics. Moreover, readers will find this edition to be substantially improved from past editions in both content and physical appearance."--Doody's Review ServiceThe most universally respected and read medical text in all of pharmacology, Goodman & Gilman's The Pharmacological Basis of Therapeutics represents the pinnacle of authority and accuracy in describing the actions and uses of therapeutic agents in relation to physiology and pathophysiology. Goodman & Gilman's careful balance of basic science and clinical application has guided thousands of practitioners and students to a clear understanding of the drugs essential to preventing, diagnosing, and treating disease.Enriched by a new full-color presentation and updated to reflect all critical new developments in drug action and drug-disease interaction, the twelfth edition includes more than 440 color illustrations depicting key principles and actions of specific pathways and therapeutic agents. The companion DVD includes all the images and tables in the text along with narrated animations.Goodman & Gilman's The Pharmacological Basis of Therapeutics, 12e is divided into nine sections, covering:General PrinciplesNeuropharmacologyModulation of Cardiovascular FunctionInflammation, Immunomodulation, and HematopoiesisEndocrine PharmacologyGastrointestinal PharmacologyChemotherapy of Infectious DiseaseChemotherapy of Neoplastic DiseasesSpecial Systems PharmacologyMore than a textbook, Goodman & Gilman's is a working template for the effective and rational prescribing of drugs in daily practice.
ContributorsConsultants to the EditorsPrefacePreface to the First EditionSECTION I: GENERAL PRINCIPLES1. Drug Invention and the Pharmaceutical Industry, Suzanne M. Rivera and Alfred Goodman Gilman2. Pharmacokinetics: The Dynamics of Drug Absorption, Distribution, Metabolism, and Elimination, Iain L. O. Buxton and Leslie Z. Benet3. Pharmacodynamics: Molecular Mechanisms of Drug Action, Donald K. Blumenthal and James C. Garrison4. Drug Toxicity and Poisoning, Kevin C. Osterhoudt and Trevor M. Penning5. Membrane Transporters and Drug Response, Kathleen M. Giacomini and Yuichi Sugiyama6. Drug Metabolism, Frank J. Gonzalez, Michael Coughtrie, and Robert H. Tukey7. Pharmacogenetics, Mary V. Relling and Kathleen M. GiacominiSECTION II: NEUROPHARMACOLOGY8. Neurotransmission: The Autonomic and Somatic Motor Nervous Systems, Thomas C. Westfall and David P. Westfall9. Muscarinic Receptor Agonists, Joan Heller Brown and Nora Laiken10. Anticholinesterase Agents, Palmer Taylor11. Agents Acting at the Neuromuscular Junction and Autonomic Ganglia, Ryan E. Hibbs and Alexander C. Zambon12. Adrenergic Agonists and Antagonists, Thomas C. Westfall and David P. Westfall13. 5-Hydroxytryptamine (Serotonin) and Dopamine, Elaine Sanders-Bush and Lisa Hazelwood14. Neurotransmission and the Central Nervous System, Perry B. Molinoff15. Drug Therapy of Depression and Anxiety Disorders, James M. O'Donnell and Richard C. Shelton16. Pharmacotherapy of Psychosis and Mania, Jonathan M. Meyer17. Hypnotics and Sedatives, S. John Mihic and r. Adron Harris18. Opioids, Analgesia, and Pain Management, Tony L. Yaksh and Mark S. Wallace19. General Anesthetics and Therapeutic Gases, Piyush M. Patel, Hemal H. Patel, and David M. Roth20. Local Anesthetics, William A. Catteral nad Kenneteh Mackie21. Pharmacotherapy of the Epilepsies, James O. McNamara22. Treatment of Central Nervous System Degenerative Disorders, David G. Standaert and Erik D. Roberson23. Ethanol and Methanol, Marc A. Schuckit24. Drug Addition, Charles P. O'Brien25. Regulation of Renal Function and Vascular Volume, Robert F. Reilly and Edwin K. Jackson26. Renin and Angiotensin, Randa Hilal-Dandan27. Treatment of Myocardial Ischemia and Hypertension, Thomas Michel and Brian B. Hoffman28. Pharmacotherapy of Congestive Heart Failure, Bradley A. Maron and Thomas P. Rocco29. Anti-Arrhythmic Drugs, Kevin J. Sampson and Robert S. Kass30. Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs, Jeffrey I. Weitz31. Drug Therapy for Hypercholesterolemia and Dyslipiedmia, Thomas P. BersotSECTION IV: INFLAMMATION, IMMUNOMODULATION, AND HEMATOPOIESIS32. Histamine, Bradykinin, and Their Antagonists, Randal A. Skidgel, Allen P. Kaplan, and Ervin G. Erdoes33. Lipid-Derived Autacoids: Eicosanoids and Platelet-Activating Factor, Emer M. Smyth, Tilo Grosser, and Garret A. Fitzgerald34. Anti-inflammatory, Antipyretic, and Analgesic Agents; Pharmacology of Gout, Tilo Grosser, Emer Smyth, and Garret A. FitzGerald35. Immunosupressants, Tolerogens, and Immunostimulants, Alan M. Krensky, William M. Bennett, and Flavio Vincenti36. Pulmonary Pharmacology, Peter J. Barnes37. Hematopoietic Agents: Growth Factors, Minerals, and Vitamins, Kenneth Kaushansky and Thomas J. KippsSECTION V: HORMONES AND HORMONE ANTAGONISTS38. Introduction to Endocrinology: The Hypothalamic-Pituitary Axis, Keith L. Parker and Bernard P. Schimmer39. Thyroid and Anti-Thyroid Drugs, Gregory A. Brent and Ronald J. Koenig40. Estrogens and Progestins, Ellis R. Levin and Stephen R. Hammes41. Androgens, Peter J. Snyder42. ACTH, Adrenal Steroids, and Pharmacology of the Adrenal Cortex, Bernard P. Schimmer and John W. Funder43. Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia, Alvin C. Powers and David D'Alessio44. Agents Affecting Mineral Ion Homeostatis and Bone Turnover, Peter A. FriedmanSECTION VI: DRUGS AFFECTING GASTROINTESTINAL FUNCTION45. Pharmacotherapy of Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease, John L. Wallace and Keith A. Sharkey46. Treatment of Disorders of Bowel Motility and Water Flux: Anti-Emetics; Agents Used in Biliary and Pancreative Disease, Keith A. Sharkey and John L. Wallace47. Pharmacotherapy of Inflammatory Bowel Disease, John L. Wallace and Keith A. Sharkey48. General Principles of Antimicrobial Therapy, Tawanda Gumbo49. Chemotherapy of Malaria, Joseph M. Vinetz, Jerome Clain, Viengngeun Bounkeua, Richard T. Eastman, and David Fidock50. Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other Protozoal Infections, Margaret A. Phillips, Samuel L. Stanley, Jr.51. Chemotherapy of Helminth Infections, James McCarthy, Alex Loukas, and Peter J. Hotez52. Sulfonamides, Trimethoprim-Sulfamethoxazole, Quinolones, and Agents for Urinary Tract Infections, William A. Petri, Jr.53. Penicillins, Cephalosporins, and Other ss-Lactam Antibiotics, William A. Petri, Jr.54. Aminoglycosides, Conan MacDougall and Henry F. Chambers55. Protein Synthesis Inhibitors and Miscellaneous Antibacterial Agents, Conan MacDougall and Henry F. Chambers56. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy, Tawanda Gumbo57. Antifungal Agents, John E. Bennett58. Antiviral Agents (Nonretroviral), Edward P. Acosta and Charles Flexner59. Antiretroviral Agents and Treatment of HIV Infection, Charles Flexner60. General Principles of Cancer Chemotherapy, Bruce A. Chabner61. Cytotoxic Agents, Bruce A. Chabner, Joseph Bertino, James Cleary, Taylor Ortiz, Andrew Lane, Jeffrey G. Supko, and David Ryan62. Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines, Bruce A. Chabner, Jeffrey Barnes, Joel Neal, Erin Olson, Hamza Mujagic, Lecia Sequist, Wynham Wilson, Dan L. Longo, Constantine Mitsiades, and Paul Richardson63. Natural Products in Cancer Chemotherapy: Hormones and Related Agents, Beverly Moy, Paul Goss, Richard J. Lee, and Matthew SmithSECTION IX: OPHTHALMOLOGY64. Ocular Pharmacology, Jeffrey D. Henderer and Christopher J. Rapuano65. Dermatological Pharmacology, Craig Burkhart, Dean Morrell, and Lowell Goldsmith66. Contraception and Pharmacotherapy of Obstetrical and Gynecological Disorders, Bernard P. Schimmer and Keith L. Parker67. Environmental Toxicology: Carcinogens and Heavy Metals, Michael C. Byrns and Trevor M. PenningAPPENDICESI. Principles of Prescription Order Writing and Patient Compliance, Iain L.O. BuxtonII. Design and Optimization of Dosage Regimens: Pharmacokinetic Data, Kenneth E. Thummel, Danny D. Shen, and Nina IsoherranenIndexNER(01): WOW