Description
Epigenetic Therapy by Phytochemicals in Lung Cancer provides a comprehensive exploration of the intersection between cancer epigenetics and phytotherapy, focusing on lung cancer. The book emphasizes the role of epigenetic alterations in cancer progression and presents phytochemicals as promising agents capable of reversing these changes, thereby offering innovative therapeutic strategies. The content examines the mechanisms by which epigenetic modifications, such as DNA methylation and histone modification, contribute to lung cancer. It details specific phytochemicals—like curcumin, resveratrol, and quercetin—and their potential to modulate these pathways, while discussing clinical applications, challenges, and future research directions. For academics, this book equips researchers and healthcare professionals with evidence-based insights into alternative cancer therapies, enhancing understanding of multi-targeted approaches. It serves as a valuable reference for teaching and further research, promoting a more inclusive perspective in cancer care and addressing disparities in treatment access and efficacy.- Collates current research on epigenetic changes in lung cancer and how specific phytochemicals interact with these mechanisms to halt or reverse tumor progression- Discusses the therapeutic potential of phytochemicals as low-toxicity alternatives or adjuncts to conventional lung cancer treatments- Identifies gaps in current research and outlines promising areas for study, helping researchers and practitioners pinpoint future opportunities in developing effective phytochemical-based therapies
Table of Contents
Part I: Introduction to lung cancer and epigenetics1 Lung cancer2 The role of epigenetic alterations in lung cancer progression3 Epigenetic therapy by phytochemicals in lung cancer: Mechanism, therapeutic potential, and clinical implicationsPart II: Phytochemicals as epigenetic modulators4 Introduction to phytochemicals with epigenetic activity5 DNA methylation modulation by phytochemicals6 Nature's epigenetic tools: Histone modification control by phytochemicals in lung cancer7 Impact of phytochemicals on noncoding RNAs in lung cancerPart III: Phytochemicals in lung cancer therapy—Mechanisms and evidence8 Polyphenols as epigenetic modulators: Curcumin, resveratrol, and quercetin9 Flavonoids and epigenetic therapy in lung cancer10 Terpenoids and their role in lung cancer epigenetic modulation11 Alkaloids and lung cancer epigenetics: Mechanistic insights and case studiesPart IV: Clinical implications and future directions12 Preclinical and clinical trials of phytochemicals in lung cancer epigenetics13 Insights into clinical trials and real-world applications of phytochemicals14 Challenges in phytochemical-based epigenetic therapy15 Formulation and delivery systems for phytochemical-based epigenetic drugs16 Combination therapies: Phytochemicals with conventional lung cancer therapies17 Conclusion and future perspectives in epigenetic phytotherapy for lung cancer18 Cancer immunotherapy, including CAR-T cell therapy and immune checkpoint inhibitors
