Description
Toxicological Survey of African Medicinal Plants, Second Edition bridges traditional knowledge with modern science, providing a comprehensive and detailed overview of toxicological studies related to traditionally used African medicinal plants with special emphasis on practical insights and scientifically validated methodologies, and tools used for data collection and interpretation. Completely revised and updated, the book considers the physical parameters of novel plants and their effect on specific areas of the body and overall human health, including chapters dedicated to genotoxicity, hepatotoxicity, nephrotoxicity, cardiotoxicity, neurotoxicity, and specific organs and systems.The new edition also considers advances in omics approaches and the increased use of advanced analytical techniques to understand plant toxicity and improved the identification of toxic compounds in medicinal plants. With contributions from a distinguished team of researchers in the field, this book is an invaluable resource for researchers, advanced students and postgraduates, industry professionals, and policymakers who require an integrated understanding of toxicology, pharmacology, ethnopharmacology, as well as regulatory and policy frameworks for African medicinal plants.- Provides a completely updated and revised resource with up-to-date toxicological data on African medicinal plants and families- Offers a critical review and updates of the methods used in a toxicological survey of medicinal plants- Highlights African plants that are pharmacologically active, coupled with low toxicity- Examines safe botanicals based on their investigated toxicity profiles, which can be recommended for further preclinical and clinical studies in the context of drug development- Integrates new data and topics such as toxicogenomics and herbal-drug interactions into relevant chapters
Table of Contents
1. Toxicological Societies in Africa and Their Implication in Policy Making and Living Conditions2. Advancements in Managing Ethical Concerns Regarding Animal Use in Toxicological Research in Africa3. Critical Review of the Guidelines and Methods in Toxicological Research in Africa: New Advances4. Discordant Results in Plant Toxicity Studies in Africa: Established Standards and Recent Advances5. Acute and Subacute Toxicities of African Medicinal Plants6. Subchronic and Chronic Toxicities of African Medicinal Plants: An Updated Review7. Toxic Plants Used in African Traditional Medicine: An Update8. Cytotoxicity of African Medicinal Plants Against Normal Animal and Human Cells: An Updated Review9. Genotoxicity and Teratogenicity of African Medicinal Plants: An Updated Review10. Mutagenicity and Carcinogenicity of African Medicinal Plants: An Update11. Hepatotoxicity and Hepatoprotective Effects of African Medicinal Plants: An Update From 2014 To Present12. Nephrotoxicity and Nephroprotective Potential of African Medicinal Plants: An Updated Review13. Cardiotoxicity and Cardioprotective Effects of African Medicinal Plants14. Neurotoxicity and Neuroprotective Effects of African Medicinal Plants15. Toxicity and Beneficial Effects of Some African Plants on the Reproductive System16. Update on African Plants Relevant to Dermatology and Ophthalmology17. Toxicity and Protective Effects of African Medicinal Plants on the Spleen and Lung: An Updated Review18. Safe African Medicinal Plants for Clinical Studies19. Update on the Harmful and Protective Effects of Terpenoids from African Medicinal Plants20. Harmful and Protective Effects of Phenolic Compounds from African Medicinal Plants21. Health Effects of Alkaloids from African Medicinal Plants: A Review from 2014 to Present 22. Physical, Hematological, and Histopathological Signs of Toxicity Induced by African Medicinal Plants23. Biochemical Parameters in Toxicological Studies in Africa: An Update for their Significance, Principle of Methods, Data Interpretation, and Use in Plant Screenings
