Description
Thoroughly revised, updated, and extended by experts in their fields, and edited by Professors Kevin Taylor and Michael Aulton, Aulton's Pharmaceutics, 7th Edition, comprehensively covers the science and practice of formulation, pharmaceutical manufacturing, and drug delivery. This essential pharmaceutics textbook offers a complete course in one book for students in all years of undergraduate pharmacy and pharmaceutical sciences degrees. It is also an invaluable resource for students undertaking postgraduate studies in the pharmaceutical sciences, practitioners in the pharmaceutical and associated industries, and those working in hospital pharmacy technical services and medicines regulation. It features a clear, readily accessible writing style, extensive illustrations, and numerous tables, figures, and information boxes to assist with the understanding of this complex subject area.- Provides an essential companion to the entire pharmaceutics curriculum from day one until the end of the course—written specifically for those new to the design and manufacture of dosage forms- Contains updates from cover to cover, with the addition of new chapters, to reflect advances in formulation and drug delivery science, pharmaceutical manufacturing and medicines regulation- Includes updated information regarding COVID in nanomedicines and biologicals.- Covers relevant pharmaceutical science throughout, including the science of formulation and drug delivery- Reflects current practices and future applications of formulation and drug delivery science to small drug molecules, biotechnology products, and nanomedicines- Includes key points boxes for quick summaries of important information, and more than 400 multiple-choice questions online for self-assessment and review
Table of Contents
PART 1 Scientific principles of dosage form design1 Design of dosage forms2 Dissolution and solubility3 Properties of solutions4 Surfaces and interfaces5 Disperse systems6 Rheology7 KineticsPART 2 Particle science and powder technology8 Solid-state properties9 Particle size analysis10 Particle size reduction and size separation11 Mixing12 Powder flowPART 3 Pharmaceutical microbiology and sterilization13 Fundamentals of microbiology14 Pharmaceutical applications of microbiological techniques15 Action of physical and chemical agents on microorganisms16 Principles of sterilization17 Sterilization in practicePART 4 Biopharmaceutical principles of drug delivery18 Introduction to biopharmaceutics19 Gastrointestinal tract – physiology and drug absorption20 Bioavailability – physicochemical, dosage form and formulation factors21 Assessment of biopharmaceutical properties22 Dosage regimensPART 5 Dosage form design and manufacture23 Pharmaceutical preformulation24 Solutions25 Clarification26 Suspensions27 Emulsions and creams28 Ointments, pastes, gels, cutaneous patches and topical sprays29 Powders, granules and granulation30 Drying31 Tablets and compaction32 Modified-release oral drug delivery33 Coating of tablets and multiparticulates34 Continuous manufacturing of tablets35 Hard capsules36 Soft capsules37 Dissolution testing of solid oral dosage forms38 Parenteral drug delivery39 Pulmonary drug delivery40 Nasal drug delivery41 Ocular drug delivery42 Otic drug delivery43 Topical and transdermal drug delivery44 Rectal and vaginal drug delivery45 Preparation and delivery of biopharmaceuticals46 Pharmaceutical nanotechnology and nanomedicines47 Radiopharmaceuticals48 The formulation and manufacture of plant medicines49 Design and administration of medicines for paediatric and geriatric patientsPART 6 Packaging, stability and pharmaceutical regulation50 Packaging51 Chemical stability in dosage forms52 Microbial contamination, spoilage and preservation of medicines53 Product stability and stability testing54 Pharmaceutical quality: the application of pharmaceutics in medicines regulation
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