Description
More than 60 years since its first publication, Clinical Pharmacology remains an invaluable textbook that no clinician or prescriber, medical or pharmacy student should be without.This highly trusted guide to drug therapy covers the key elements of therapeutic pharmacology, including health technology assessment, drug regulation, dependence and toxicology, as well as polypharmacy. The essentials of clinical pharmacology are discussed by body system, balancing science with practice to support good prescribing.The thirteenth edition of Clinical Pharmacology has been fully updated to suit today's context and therapeutic settings.- An ideal study guide for medical students sitting the PSA exams and pharmacy students sitting MPharm exams- Fully updated to encompass contemporary issues such as comorbidities and polypharmacy- Provides the evidence base for drug therapy and good prescribing in modern therapeutic settings- Easy to navigate - covers all major therapeutic topics by body system- Chapter synopses, definitions, tips and brief explanation boxes assist with learning and revision- Covers resource poor situations with a focus on practical prescribing and health technology assessment- Includes case studies, interesting histories, etymologies and provenances of terms throughout
Table of Contents
Section 1: General- Clinical pharmacology- Topics in drug therapy- Discovery and development of drugs- Evaluation of drugs in humans- Health technology assessment for pharmaceutical products- Regulation of medicines- Classification and naming of drugs- Polypharmacy and medicines optimisationSection 2: From pharmacology to toxicology- General pharmacology- Unwanted effects and adverse drug reactions- Poisoning, overdose, antidotes- Drug dependenceSection 3: Infection and inflammation- Chemotherapy of infections- Antibacterial drugs- Chemotherapy of bacterial infections- Viral, fungal, protozoal and helminthic infections- Therapeutics for COVID-19- Drugs for inflammation and joint disease- Drugs and the skinSection 4: Nervous system- Pain and analgesics- Anesthesia and neuromuscular block- Psychotropic drugs- Neurological disorders – epilepsy, Parkinson's disease and multiple sclerosisSection 5: Cardiorespiratory and renal systems- Cholinergic and antimuscarinic (anticholinergic) mechanisms and drugs- Adrenergic mechanisms and drugs- Cardiovascular disease and heart failure- Cardiac arrhythmias- Hyperlipidaemias- Kidney and genitourinary tract- Respiratory systemSection 6: Blood and neoplastic disease- Drugs and haemostasis- Red blood cell disorders- Neoplastic disease and immunosuppressionSection 7: Gastrointestinal system- Oesophagus, stomach and duodenum- Intestines- Liver and biliary tractSection 8: Endocrine system, metabolic conditions- Adrenal corticosteroids, antagonists, corticotropin- Diabetes mellitus and obesity- Thyroid hormones, antithyroid drugs- Hypothalamic, pituitary and sex hormones- Vitamins, calcium and bone
