Description
Provides practical, evidence-based guidance for managing transfusion practice and patient care in patients who may require transfusion.
The rapid evolution of transfusion medicine, shaped by advances in science, technology, and global practice, demands an authoritative and up-to-date resource. Practical Transfusion Medicine, Seventh Edition, meets this need by offering a comprehensive and clinically grounded guide to the principles and practice of transfusion medicine. Building on the trusted foundations of previous editions, it balances depth of coverage with accessibility, making it an indispensable resource for trainee and practising haematologists, clinical and scientific staff working in transfusion services, and clinicians treating patients who may require transfusion.
This new edition reflects the considerable changes in the field since 2022, incorporating new sections on patient blood management, cellular and tissue therapy, and organ transplantation. A dedicated chapter on cardiorespiratory complications including transfusion-associated circulatory overload highlights their importance as a complication of transfusion, whilst the restructured clinical practice section offers a more focused approach to transfusion management across medical, surgical, and haematology patients. With contributions from leading international experts, the text provides evidence-based insights supported by numerous charts, tables, and algorithms.
Practical Transfusion Medicine, Seventh Edition:
- Integrates scientific, clinical, and regulatory perspectives with global context
- Provides detailed coverage of transfusion-associated complications and their management
- Features expanded sections on patient blood management, tissue therapy, and transplantation
- Balances comprehensive detail with clarity, offering more depth than handbooks yet more accessibility than reference tomes
- Addresses both acute clinical decision-making and long-term patient management
Practical Transfusion Medicine, Seventh Edition, is essential for postgraduate and specialist trainees in haematology preparing for examinations such as the FRCPath in the UK, as well as for trainees in the many specialties where transfusions are used. It is equally valuable as a reference tool for established clinicians treating patients requiring transfusion and for clinical and scientific staff working in transfusion services.
Table of Contents
List of Contributors viii
Preface to the Seventh Edition xv
Part I Introduction 1
1 Past, Present and Future of Transfusion Medicine 1
Richard M. Kaufman
Part II Basic Principles of Immunohaematology and Transplantation 10
2 Essential Immunology for Transfusion Medicine 10
Connie M. Arthur and Sean R. Stowell
3 Red Blood Cell Antigens and Antibodies 19
Jennifer R. Hagman and Jill R. Storry
4 Platelet, Neutrophil and Leucocyte Antigens and Antibodies 31
Louise Helander and Caroline R. Alquist
Part III Overarching Principles of Good Practice in Transfusion Medicine 46
5 Evidence-Based Transfusion Medicine 46
Adam Irving, Khai L. Chai, Susan J. Brunskill, and Zoe K. McQuilten
6 Quality Management in Transfusion Medicine 59
Sarah L. Morley, Gustavo C. Duarte, and Fidelma Murphy
7 Donors and Blood Collection 70
Marc Germain and Pierre Tiberghien
8 Principles of Patient Blood Management 82
Allison Mo and Monica B. Pagano
9 The Role of Haemovigilance in Transfusion Safety 104
Barbee I. Whitaker, Katharine A. Downes, and Johanna C. Wiersum-Osselton
10 Emergency Blood Preparedness 115
Torunn O. Apelseth and Tom Scorer
Part IV Practice in Blood Centres and Hospitals 122
11 Blood Donation Testing and the Safety of the Blood Supply 122
Agbonbhaselena Omonua, Susan R. Brailsford, and Stephen Thomas
12 Production and Storage of Blood Components 132
Denese Marks and Susanne Marschner
13 Pre-transfusion Testing and the Selection of Products for Transfusion 148
Chris Hogan and Alison Davies
14 Hospital Oversight of Transfusion Safety and the Appropriate Use of Blood 159
Nicole Relke, Susan Nahirniak, and Andrew W. Shih
Part V Clinical Transfusion Practice 178
15 Inherited and Acquired Red Cell Disorders 178
Raisa Balbuena-Merle, Christopher A. Tormey, and David Raggay
16 Inherited and Acquired Platelet Disorders 190
Anand Padmanabhan and Dong Chen
17 Inherited and Acquired Disorders of Coagulation 204
Emmanuel J. Favaloro, Marian Rollins-Raval, and Rajiv Pruthi
18 Transfusion in Patients with Major Haemorrhage 222
Aaron Stansbury Hess
19 Elective Transfusions 233
Simon J. Stanworth and Akshay Shah
20 Obstetric Transfusion Medicine 243
Anna Parakh, Erin O'Reilly, and Helen Savoia
21 Neonatal, Infant and Paediatric Transfusion 255
Anne M. Kelly
22 Plasma Derivatives 267
Matea Vinkovi? Vlah, Anja Mäkelburg, and Cynthia So-Osman
23 Therapeutic Apheresis 279
Andrew D. Johnson and Nicole D. Zantek
Part VI Complications of Transfusion 292
24 Approach to the Investigation and Management of a Patient with a Suspected Transfusion Reaction 292
HyoJeong Han and Meghan Delaney
25 Acute Haemolytic Transfusion Reactions 306
Courtney K. Hopkins and Rim Abdallah
26 Allergic and Anaphylactic Transfusion Reactions 318
Liz Marinaro and Ralph Vassallo
27 Respiratory Complications of Transfusion 326
Tom Latham, Rick Kapur, Alexander Vlaar, and Paula HB Bolton-Maggs
28 Complications of Transfusion: Bacterial Sepsis 339
Michel-Andrés García-Otálora, Sylvia Ighem-Chi, and Sandra Ramírez-Arcos
29 Delayed Complications of Blood Transfusion 351
France Pirenne and Mariane de Montalembert
30 Transfusion-Transmitted Infections – Pathogens of Concern 364
Brian Custer
31 Transfusion-Transmitted Infections – Interventions and Measuring Risk 373
Brian Custer
Part VII Cellular Therapy and Transplantation 382
32 Haematopoietic Cell Transplantation 382
Laura Connelly-Smith
33 Cellular Immunotherapy 397
Daniel North, Louis Peters, and Ronjon Chakraverty
34 Tissue Banking 409
Clint S. Schmidt, Kristen L. Rodriguez, Michael C. Deeds, and Eapen K. Jacob
Index 417
