Mitochondria and Cancer : From Basic Science to Clinical Applications – Understanding Pathogenesis, Therapy Resistance, and Disease Relapse

著者名：Taghizadeh-Hesary, Farzad (EDT)/Ashique PhD, Sumel (EDT)/Behnam MD, PhD, Babak (EDT)/Vliora PhD, Maria (EDT)

Elsevier（2026/02/14発売）

• 言語：ENG
• ISBN：9780443405358
• eISBN：9780443405365

Description

Mitochondria and Cancer: From Basic Science to Clinical Applications—Understanding Pathogenesis, Therapy Resistance, and Disease Relapse offers comprehensive perspectives about the role of mitochondria in cancer biology and treatment. This book integrates fundamental scientific knowledge with clinical relevance, presenting recent findings that will engage oncology researchers and provide valuable recommendations for cancer prevention and prognosis. In response to the rising global cancer incidence, this book serves as a comprehensive guide to mitochondrial metabolism in oncology, furthering cancer study and management. It explores a wide range of topics that highlight the multifaceted role of mitochondria in cancer, including tumor microenvironment, cancer stem cells, microbiota, resistance mechanisms, mitochondria-enhancing strategies, and targeted therapies. It includes technical details, research findings, and discussions on the implications of mitochondrial research in cancer treatment and management. Its distinguishing aspects include its comprehensive coverage and diverse perspectives from global experts, providing a well-rounded view of current research.- Delivers an in-depth analysis of how mitochondrial alterations contribute to cancer formation, disease progression, and resistance to conventional and targeted therapies- Presents comprehensive insights into the dynamic interactions between mitochondria in cancer cells, tumor microenvironment, and microbiota, highlighting their collective influence on cancer progression and therapeutic outcomes- Combines fundamental scientific knowledge with clinical relevance, covering a wide array of topics from mitochondrial metabolism to innovative therapeutic strategies

Table of Contents

1. Mitochondria: Origin, Structure, and Function2. Mitochondrial Metabolism and Trafficking in Cancer3. Mitochondrial Genome and Cancer4. Mitochondrial-nuclear Crosstalk and Its Role in Cancer5. Mitochondria and Tumor Microenvironment6. Mitochondria and Cancer Stem Cells7. Mitochondria, Exosome, Cancer8. Mitochondria, Microbiota, Cancer9. MiRNAs and Their Impacts on Cancer Cell's Mitochondria10. Mitochondria and Cancer Prevention11. Mitochondria and Cancer Diagnosis12. Mitochondrial Metabolism as a Prognostic Biomarker (Mitochondria and Cancer Progression)13. Mitochondria, Tumor Microenvironment, and Radioresistance14. Mitochondria and Resistance to Chemotherapy15. Mitochondria and Resistance to Targeted Therapies16. Mitochondria and Resistance to Immunotherapy17. Mitochondria Enhancing Strategies in Cancer18. Advances in Targeted Anti-mitochondrial Therapies19. Applying Magnetic Fields to Target Mitochondria20. what the Artificial Intelligence (AI) Proposes for the Mitochondria Role in Cancer