The Gut Microbiome in Precision Medicine : From Research to Clinical Practice

著者名：Ahmad PhD, S Rehan (EDT)

Academic Press（2026/03/18発売）

• 言語：ENG
• ISBN：9780443404832
• eISBN：9780443404849

Description

The Gut Microbiome in Precision Medicine: From Research to Clinical Practice explores the significant role of the gut microbiome in health and disease, particularly within gastrointestinal conditions such as inflammatory bowel disease, irritable bowel syndrome, and colorectal cancer. It covers how understanding and analyzing the gut microbiome can lead to personalized treatments, dietary plans, and precision medicine approaches in gastroenterology. Chapters explore multi-omics integration, examining complex techniques for gut microbiome profiling, including genomics, transcriptomics, proteomics, and metabolomics. Users will find updates on microbiome-based interventions, such as probiotics, prebiotics, and personalized nutrition that highlight practical applications in gastrointestinal disease management. Real-world examples and case studies discuss strategies for overcoming barriers to implementing microbiome analysis. Additionally, it addresses the challenges and opportunities of implementing microbiome analysis in clinical practice, with a special emphasis on its implications for developing countries. Finally, the book covers emerging technologies in microbiome research and their applications in gastroenterology, emphasizing future directions and research priorities.- Helps readers gain a comprehensive understanding of the latest gut microbiome research and its impact on precision medicine, covering foundational concepts, advanced methodologies, and cutting-edge technologies- Provides practical insights for healthcare professionals on integrating personalized gut microbiome profiling into clinical practice to design targeted treatment plans and dietary interventions for improved patient outcomes- Allows researchers to explore new research directions and methodologies, including multi-omics approaches, microbiome engineering, and microbiome-driven drug discovery

Table of Contents

Section I: Introduction to the Microbiome and Precision Medicine1. Definition and Importance of the Human Microbiome2. Precision Medicine in Gastroenterology3. Foundations of the Gut Microbiome4. The Gut Microbiome: Composition, Diversity, and Influencing Factors5. Epigenetic Influences of the Gut MicrobiomeSection II: Multi-omics Integration: Unraveling the Complexities of the Gut Microbiome6. Fundamentals of Multi-omics in Microbiome Research7. Advanced Multi-omics Technologies in Gut Microbiome Research8. Challenges in Integration of Multi-omics in Gut Microbiome9. Comprehensive Analysis of the Gut Microbiome10. Challenges and Limitations of Microbiome Analysis11. Advanced Methods and Technological Advances in Personalized Microbiome Research12. Precision Profiling for Tailored Health Solutions13. Standardization and Quality Control in Microbiome Analysis14. Microbiome Biomarkers and Multi-omics Approaches in Precision Medicine15. Definition and Importance of the Microbiome Biomarkers16. Overview of Microbiome Biomarkers and Their Applications in Gastroenterology17. Personalized Gastroenterology: Inflammatory Bowel Disease18. Role of the Gut Microbiome in the Pathogenesis of IBD19. Microbiome-Based Biomarkers for IBD Diagnosis and Prognosis20. Microbiome-Based Interventions for IBD Treatment21. Personalized Gastroenterology: Irritable Bowel Syndrome22. Role of the Gut Microbiome in the Pathogenesis of IBS23. Microbiome-Based Biomarkers for IBS Diagnosis24. Microbiome-Based Interventions for IBS Management25. Personalized Gastroenterology: Colorectal Cancer26. Role of the Gut Microbiome in the Development of Colorectal Cancer27. Microbiome-Based Biomarkers for Colorectal Cancer Screening and Early Detection28. Microbiome-Based Interventions for Colorectal Cancer Prevention and TreatmentSection III: Microbiome-Based Interventions: Probiotics and Prebiotics29. Overview of Probiotics and Prebiotics30. Mechanisms of Action of Probiotics and Prebiotics31. Evidence for the Use of Probiotics and Prebiotics in Gastrointestinal Diseases32. Personalized Nutrition and the Microbiome33. Role of Diet in Shaping the Gut Microbiome34. Personalized Nutrition Plans Based on Gut Microbiome Analysis35. Examples of Successful Personalized Nutrition Interventions for Gastrointestinal Diseases36. Implementing Microbiome Analysis in Clinical Practice37. Challenges and Barriers to Implementing Microbiome Analysis in Clinical Practice38. Implementing Microbiome Analysis in Clinical Practice: Overcoming Challenges39. Case Studies of Successful Implementation of Microbiome Analysis in Clinical PracticeSection IV: Challenges and Opportunities of Personalized Gastroenterology in Developing Countries40. Unique Challenges Faced by Developing Countries in Implementing Microbiome-Based Interventions41. Personalized Medicine in Gastroenterology42. Examples of Successful Microbiome-Based Interventions in Developing Countries43. Barriers to Implementation in Precision Medicine44. Bioethical Challenges in the Era of Precision Medicine45. Artificial Intelligence in Precision Medicine: Enhancing Predictive Analytics46. CRISPR and Genome Editing: Precision Tools for Personalized TherapiesSection V: Future Directions and Research Priorities in Gut Microbiome Personalized Medicine47. Potential Applications of Microbiome Research in Other Areas of Gastroenterology48. Collaboration and International Efforts to Advance the Field of Precision Gastroenterology