Description
Advances in Microscale Electro- and Liquid Phase-Based Separation Techniques summarizes Microscale separation techniques characterized by fast, high resolution, and high efficiency with very reduced sample and solvent consumption. The book summarizes the existing body of knowledge, including hyphenated version to mass spectrometry (cLC-MS), capillary electrophoresis (CE), capillary zone electrophoresis (CZE and CZE-MS), micellar electrokinetic capillary chromatography (MEKC), capillary gel electrophoresis (CGE), capillary isoelectric focusing (CIEF), capillary isotachophoresis (CITP), capillary electrochromatography (CEC), microfluidics, and microchips. It then demonstrates the applicability of these techniques to existing and future problems in the analysis of complex mixtures of biochemicals, pharmaceuticals, environmental, and natural products.This book will be valuable to separation scientists, applications scientists, and technicians in industrial outlets, including those in pharmaceuticals, biomedicals, biotechnologies, and food and environmental industries. Students and professors who study separation techniques will also benefit greatly from the book's content.- Summarizes a wide array of microscale separation techniques- Demonstrates the applicability of microscale separation for the reduction of hazardous waste in numerous industries- Addresses current and future problems in the field of microscale separation
Table of Contents
Part I: Capillary Electrophoresis (CE)1. Fundamentals of capillary electrophoresis2. Instrumentation of capillary electromigration methods, Optical Detection3. Recent trends in C4D for capillary and microchip electrophoresis and its applications4. Capillary gel electrophoresis5. Capillary Zone Electrophoresis6. Surfactants and other Additives for Micellar Electrokinetic Capillary Chromatography7. Capillary Isoelectric Focusing: theory, instrumentation, applications, and limitations8. Capillary Isotachophoresis9. Capillary Electrophoresis-Mass Spectrometry10. Noise reduction techniques for capillary electrophoresis and electrochromatography11. Capillary electrophoresis in the control of residues and contaminants in food12. Capillary electrophoresis in pharmaceutical analysis13. Is capillary electrophoresis well adapted for lipid separations?Part II: Capillary Electrochromatography (CEC)14. Basic principles and operational aspects of capillary electrochromatography15. Theory and practice of capillary electrochromatography–mass spectrometry: opportunities and challenges16. Applications of capillary electrochromatographyPart III: Capillary Liquid Chromatography17. Fundamentals of capillary liquid chromatography—basic principles, advantages and limitations18. Instrumentation of capillary liquid chromatography19. Capillary liquid chromatography-mass spectrometry: a case study on glycans and glycoconjugates20. Applications of capillary liquid chromatographyPart IV: Microfluidics and Microchips-Based Techniques21. Microchip capillary electrophoresis and capillary electrochromatography22. Fabrication methods for microchip capillary electrophoresis and capillary electrochromatography and their coupling to mass spectrometry23. Instrumentation for microfluidic capillary liquid chromatography24. Nanoscale electrophoresis of biomolecules
