Basics in Amino Acid Metabolism in Humans in Health and Disease

著者名：Holeček MD, PhD, Milan

Academic Press（2025/12/03発売）

• 言語：ENG
• ISBN：9780443445347
• eISBN：9780443445354

Description

Basics in Amino Acid Metabolism in Humans in Health and Disease summarizes the significance of amino acids and their metabolism. This book provides a single source of information bringing together a wide variety of research on the subject, explaining the rationality and risks of using some amino acids as dietary supplements. The first chapters describe amino acids' structure, classification, and transport across cell membranes and their role in protein synthesis, gluconeogenesis, and ketogenesis. The central part of the book is focused on the role of individual amino acids in the synthesis of various biologically essential substances and their metabolism in acquired and hereditary diseases. The following chapters are dedicated to the role of particular organs, such as the small intestine, intestinal microbiota, liver, muscle, kidneys, brain, adipose tissue, and lungs. The next sections are focused on amino acid metabolism under various physiological (food intake, starvation, exercise, and elderly) and pathological (systemic inflammatory response, cirrhosis, diabetes, chronic renal insufficiency, and cancer) conditions. The last chapter summarizes the benefits and potential adverse effects of increased intake of individual amino acids. The author, Professor Milan Holeček, has been studying and researching in the area for over 40+ years. "Basics in Amino Acid Metabolism in Humans in Health and Disease" is written for healthcare professionals, primarily nutritionists, specialists in intensive metabolic care, clinical nutrition, diabetology, hepatology, gerontology, gastroenterology, nephrology, and oncology.- Explains the physiological and clinical significance of amino acid metabolism in humans- Focuses on the clinical and nutritional applications of amino acids as dietary supplements- Includes images detailing the differences in amino acid concentrations in blood entering and leaving a specific organ

Table of Contents

CHAPTER 1 IntroductionCHAPTER 2 Structure and classification of amino acidsCHAPTER 3 Amino acid transport through cell membranesCHAPTER 4 Basic chemical reactionsCHAPTER 5 Amino acids and proteins in foodCHAPTER 6 AmmoniaCHAPTER 7 Glucogenic and ketogenic amino acidsCHAPTER 8 Protein synthesis, proteolysis, and proteinCHAPTER 9 Metabolism of individual amino acids in health and diseaseCHAPTER 10 Peptides, purines, and pyrimidinesCHAPTER 11 Notes on the specific role of individual organs in amino acid metabolismCHAPTER 12 Amino acid metabolism under various physiological conditionsCHAPTER 13 Amino acid metabolism in diseaseCHAPTER 14 Adverse effects of amino acids used as a dietary supplement