Description
Chemoresistance in Glioblastoma: Understanding and Management gives clear insights into the detailed characteristic aspects of glioblastoma disease and the different therapeutic targets that are employed in reducing resistance to chemotherapeutic agents. The book delves deep into the root causes of multidrug resistance and the quest for novel molecular targets among growth factors, receptors, signal transduction proteins, microRNAs, transcription factors, proto-oncogenes, and tumor suppressor genes. In addition, it gives insights on the pathological and molecular features of glioblastoma and the role of cancer stem cells in the resistance to chemo and immunotherapy.While designed as a comprehensive guide, the book also serves as a valuable reference for professionals seeking to deepen their understanding, refine their skills, and explore new avenues within chemoresistance.- Offers practical guidance for diagnosing and treating chemoresistance in glioblastoma- Provides evidence-based information to formulate effective strategies for chemoresistance in glioblastoma- Gives a comprehensive overview of the phenomenon of multidrug resistance in glioblastomas
Table of Contents
1. Molecular Mechanisms Underlying Treatment Resistance in Glioblastoma and current therapies2. A comprehensive outline of glioblastoma and molecular chemotherapy3. Brain tumors: diagnosis and treatment4. Unveiling the Therapeutic Tapestry: mRNA and RNA Vaccines in the Nexus of Glioblastoma's Pathological and Molecular Landscae.5. Cell Cycle Arrest and Apoptosis in Glioblastoma6. Cancer stem cells in resisting chemotherapy and the recurrence of glioblastoma multiforme7. Variability in Natural Invasion of Tumor Cells Patterns in Human Glioblastoma8. Epigenome in Gliomas: Novel Targets for Therapy9. Adaptation of Mitochondria in Drug Resistance of Cancer: Frequency, Mechanisms, and Control10. Immunotherapy resistant glioblastoma.11. Dynamics of glioblastoma chemotherapy in blood-brain barrier12. Epigenetic Modifications and Therapies of Gliomas: A Precision Medicine Perspectives
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