Description
In this issue of PET Clinics, guest editors Drs. Arman Rahmim, Kuangyu Shi, and Babak Saboury bring their considerable expertise to the topic of Computational and AI Methods toward Successful Applications of Theranostics. The field of nuclear medicine is currenting undergoing a renaissance, directly related to theranostics applications, where we can "see what we treat and treat what we see" using radiopharmaceuticals that target important disease biomarkers with high sensitivity. This special issue focuses on computational and AI methods tools and techniques available and under development to enable optimal use of theranostic applications.- Contains 14 relevant, practice-oriented topics including PBPK models, digital twins, and verification, validation and uncertainty quantification (VVUQ) in theranostics; mathematical and computational nuclear oncology: tools and techniques towards optimized radiopharmaceutical therapies and theranostic digital twins; computational radiobiology; mathematical oncology, cancer evolution, and radiopharmaceutical therapy; and more- Provides in-depth clinical reviews on computational and AI methods toward successful applications of theranostics, offering actionable insights for clinical practice- Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews
Table of Contents
What Is Implementation Science: And Why It Matters for Bridging the Artificial Intelligence Innovation-to-Application Gap in Medical ImagingToward Integrated Clinical-Computational Nuclear MedicineLarge Language Models Are Reshaping Patient Data Management and Clinical Practice in Nuclear MedicineSeeing More, Treating Smarter: Role of Long-axial Field-of-view PET/CT in the Evolution of TheranosticsAdvances in SPECT and PET Reconstruction for Theranostics: From Diagnosis to TherapyArtificial Intelligence for Simplified Patient-centered Dosimetry in Radiopharmaceutical TherapiesAn Overview of Physiologically Based Pharmacokinetic (PBPK) and Population Pharmacokinetic (PopPK) Models: Applications to Radiopharmaceutical Therapies for Analysis and PersonalizationVerification, Validation, and Uncertainty Quantification (VVUQ) of Physiologically Based Pharmacokinetic Models for Theranostic Digital Twins: Toward Reliable Model-Informed Treatment Planning for Radiopharmaceutical TherapiesMathematical and Computational Nuclear Oncology: Toward Optimized Radiopharmaceutical Therapy via Digital TwinsQuantitative and Computational Radiobiology for Precision Radiopharmaceutical TherapiesA Brief History of Digital Twin TechnologyToward Digital Twins for Optimal RadioembolizationRadiopharmaceutical Therapy and Immunotherapy Combinations Utilizing Cancer Evolution and Computational Modeling in Metastatic Prostate Cancer
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