Description
Biochemical and Molecular Mechanisms of Secondary Metabolites in Metabolic Diseases explores the therapeutic potential and pharmacological roles of secondary metabolites (SMs) in managing metabolic disorders. This comprehensive volume provides a detailed examination of the biochemical pathways, molecular mechanisms, and pharmacodynamics of SMs, offering insights into their potential as future drug candidates for metabolic diseases. The book begins by explaining the differences between secondary and primary metabolites, providing a clear classification and organization of SMs. It highlights recent research on SMs, including receptor interactions and molecular signal transduction pathways, to showcase their potential as interventions against metabolic disorders. The role and mechanistic details of SMs at the molecular level are illustrated, emphasizing their pharmacological participation in treating conditions such as obesity, diabetes, cardiovascular diseases, and inflammation. This book is an essential resource for students and professionals in pharmacy, medical subjects, nursing, herbal medicine, and traditional medicine programs, aligning with curricula in medical ethnobotany, ethnopharmacology, pharmacognosy, phytochemistry, and related fields. It also serves as a valuable reference for researchers in pharmacology, biochemistry, and medicinal chemistry, as well as clinicians interested in natural product-based therapeutics for managing metabolic conditions. Additionally, graduate students, postdoctoral researchers, academics, and industry professionals working in biotechnology, pharmaceuticals, and diagnostics will find this book highly beneficial for understanding the pharmacodynamic parameters, bioavailability, and potential drug-drug or food interactions of secondary metabolites.- Explains the differences between secondary and primary metabolites, providing a clear classification and organization of secondary metabolites (SMs)- Highlights recent research on SMs, including receptor interactions and molecular signal transduction pathways, to showcase their potential as interventions against metabolic disorders- Illustrates the role and mechanistic details of SMs at the molecular level, emphasizing their pharmacological potential as future drug candidates for metabolic disorders- Addresses the educational needs of students and professionals in pharmacy, medical subjects, nursing, herbal medicine, and traditional medicine programs, aligning with curricula in medical ethnobotany, ethnopharmacology, pharmacognosy, phytochemistry, and related fields
Table of Contents
1. Introduction of Secondary Metabolites as Bioactive Compounds in Health2. Sources and Extraction Techniques for Secondary Metabolites3. Secondary Metabolites in Therapeutics: Biochemical and Pharmacological Perspectives4. Anti-Obesity Effects of Secondary Metabolites: Molecular Mechanisms and Therapeutic Potential5. Secondary Metabolites in Diabetes Management: Mechanisms of Action6. Anti-inflammatory and Antioxidant Properties of Secondary Metabolites in Metabolic Health7. Anti-Hyperlipidemic Effects of Plant-Derived Secondary Metabolites8. Metabolomics in Studying Cardiometabolic Effects of Secondary Metabolites9. Molecular Mechanisms of Secondary Metabolites in Metabolic Disorder Prevention and Treatment10. The Impact of Secondary Metabolites on Epigenetic Regulation and Gut Microbiota11. Advances in Formulation and Delivery Systems for Cardiometabolic Therapeutics12. Regulatory Hurdles in Secondary Metabolite-Based Drug Formulations
