Description
Fatigue is a prevalent problem and adequate treatment is challenging because many conditions, disorders, medications, and lifestyle factors can cause fatigue. The Scientific Basis of Fatigue combines evidence-based research and clinical treatment protocols to provide a comprehensive reference to fatigue. This book is divided into seven distinct sections, starting with an introduction section defining the distinctions between physical and mental fatigue. The second and third sections detail the various conditions in both physical and mental fatigue including COVID, Parkinson disease, and depression. The next section reviews the current research on molecular and cellular aspects and models of fatigue. The final two sections review options for diagnosis and treatments for fatigue and provides a detailed resource section for further review.- Reviews molecular and cellular aspects of chronic fatigue syndrome- Outlines fatigue in relation to various conditions including diabetes, Parkinson's disease, and stroke- Includes mini dictionary of terms and summary points for each chapter
Table of Contents
PrefaceSection 1: Fatigue In Different Conditions and Scenarios1. Fatigue in clinical conditions: Inflammatory bowel disease. A new narrative2. Fatigue related to cancer treatments3. Fatigue in systemic lupus erythematosus4. Fatigue in patients with inflammatory rheumatic diseases5. Fatigue in diverse groups: taxi drivers and beyond6. Fatigue in clinical conditions: Sjogren's syndrome7. Fatigue in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): linking in brain fog8. Fatigue in fibromyalgia: a mental and physical context9. Fatigue in chronic obstructive pulmonary disease (COPD)10. Vocal fatigue11. Work and fatigue in population cohorts: pilots12. Fatigue and quality of life in Parkinson's disease13. Fatigue in diabetes14. Fatigue in stroke: a new narrative15. Fatigue in COVID-19Section 2: Mental Fatigue 16. Mental fatigue in the postpartum scenario17. Features of mental fatigue in defined populations: subjects with psychiatric disease18. Workplace measures of mental fatigue19. Psychological perspective about mental fatigue: a focus on cognitive and motivational-affective abilities20. Mental fatigue in infertility treatment21. Psychosocial dimensions of mental fatigue22. Fatigue and the reciprocal relationship with motor imagerySection 3: Molecular And Cellular Aspects and Models23. The role of glutathione in skeletal muscle fatigue24. Muscular fatigue and molecular mechanisms: Tropomyosin receptor kinase B (TrkB) signaling25. Fatigue in inflammatory bowel disease and the role of micronutrients26. The mitochondria in fatigue syndromes27. Fatigue and catalytic autoantibodies28. Short chain fatty acids and fatigue29. Investigating fatigue in rats on high-fat regimens30. Computational modelling of fatigueSection 4: Physiological Aspects31. Temperature in the working environment and effects on fatigue32. Mental imagery of fatigue-related multisensory sensations and fMRI33. Fatigue of the respiratory muscles34. Overview of cardiorespiratory system involvement in fatigue35. Fatigue and physiology of exercise performance as a result of COVID-19Section 5: Diagnosis and Assessments36. Diagnosis and treatment of fatigue in Long COVID37. Biomarkers, fatigue and long COVID38. Questionnaires for screening fatigue: Parkinson's diseaseSection 6: Treating and Managing Fatigue39. Treating fatigue with dopaminergic regulators; a focus on s (-)-OSU6162 40. Potential of using carnosine in ameliorating fatigue41. Fatigue associated variables in multiple sclerosis and affective drug treatment42. Modulating mental fatigue: use of Creatine, Caffeine or ketones43. The Role of Bupropion in Managing Fatigue: Clinical Insights and Usage44. The Mediterranean diet and effects on fatigue45. Managing Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): a new narrative46. Resistance training: features and use in treating fatigue in cancer survivors47. Online treatment regimens in chronic fatigue syndrome48. Omega-3 Polyunsaturated Fatty Acids in Fatigue Management: Clinical Applications and MechanismsSection 7: Resources49. Resources for Fatigue



