Description
In the complex realm of our physiology, the vagus nerve stands as a silent orchestrator, influencing health and disease in ways that have long been underestimated. Vagus Nerve Stimulation delves into the profound significance of this 10th cranial nerve, tracing its course through the body and illuminating its role as a vital component of the parasympathetic nervous system. This comprehensive reference, contributed by leading experts at the forefront of medical science, unveils the groundbreaking field of vagus nerve stimulation—a non-invasive approach to harness the body's innate potential for health optimization, inflammation control, and disease modification. Contributed by leading experts in the field, this comprehensive volume serves as a compendium of current knowledge about stimulating the vagus nerve in many different disease states. This book starts with the foundational insights in Basic Science and Technical Considerations. From there, it continues to Neurologic Conditions, where chapters explore applications for epilepsy, cluster headaches, and concussions. Evolving Therapy for Neurologic Conditions introduces cutting-edge treatments for acute ischemic stroke, synaptic plasticity, and neurodegenerative disorders. The book extends into Psychiatric and Somatic Conditions, providing insights into anxiety, depression, addiction disorders, and more. Conventional Inflammatory Conditions shed light on vagus nerve stimulation's role in combatting sepsis, immune-mediated inflammatory diseases, and metabolic syndrome, among others. Concluding with a foray into Oncology, the book highlights the potential of vagus nerve stimulation in addressing the lingering effects of long covid and migraine. With an authoritative blend of scientific rigor and practical application, this reference serves as an indispensable guide to the vast landscape of vagus nerve stimulation, transforming our understanding of health and wellness.- Translates the basic science of vagus nerve stimulation into real-world clinical applications- Explains VNS anatomy and signaling through central and autonomic nervous system- Reviews VNS treatment of neurological, psychiatric, and inflammatory disorders- Extends clinical utility to cardiac, renal, and metabolic disorders.- Provides new insights to the disorder of vagus insufficiency syndrome- Explores VNS treatment for headaches, TBI, stroke, seizures, and pain.
Table of Contents
Section 1: Why is the vagus getting so much attention1. Vagus insufficiency syndrome2. Randomized controlled studies do not reflect the complexity of chronic disease, including the vagal response3. Vagus nerve stimulator (VNS)—What the surgeon needs to know4. Noninvasive vagus nerve stimulation: History, mechanisms, indications, and obstacles5. Exploring vagus nerve stimulation through the lens of the polyvagal theorySection 2: Neurological conditions6. Vagus nerve stimulation for the management of epilepsy7. Noninvasive vagus nerve stimulation in migraine treatment8. Vagal nerve stimulation in rare headache disorders9. Vagus nerve stimulation for the management of traumatic brain injurySection 3: Evolving therapy for neurologic conditions10. Vagus nerve stimulation in acute stroke: Review based on current modalities and emerging trends11. Using vagus nerve stimulation to direct synaptic plasticity and treat neurological disease12. Vagus nerve stimulation for the management of tinnitus13. Vagus nerve stimulation for the management of neurodegenerative disorders14. Vagal nerve stimulation for cognitive and performance enhancement15. Vagus nerve stimulation for the management of chronic painSection 4: Psychiatric and somatic conditions16. Vagus nerve stimulation for the management of depression and anxiety17. Application of vagal nerve stimulation to post-traumatic stress disorder18. Vagus nerve stimulation for the management of fibromyalgia19. Vagus nerve stimulation for the management of visceral pain20. Vagus nerve stimulation for the management of addiction disordersSection 5: Conventional inflammatory conditions21. Vagal nerve stimulation for the management of sepsis22. Vagus nerve stimulation for the management of immunemediated inflammatory diseases23. Vagus nerve stimulation for the management of inflammatory bowel disease and the cholinergic antiinflammatory pathway24. Clinical applications of vagal nerve stimulation for gastrointestinal motility disorders and chronic abdominal pain25. Treatment of acute asthma exacerbations with vagus nerve stimulation26. Metabolic syndrome: Understanding its root cause, and the role of macrophages and why vagus nerve stimulation may be an effective treatment27. Vagus nerve stimulation for the management of obesity, type 2 diabetes mellitus, and metabolic syndrome28. Vagus nerve stimulation and kidney function29. The neural tourniquet30. Vagus nerve stimulation for the treatment of heart failure31. Vagus nerve stimulation for long COVID32. Vagal nerve stimulation applications in oncology
