Description
Metabolomics for Personalized Vaccinology provides insight into the importance of personalized vaccines in the clinical and research environments. It explores the development of personalized vaccines, which requires in-depth knowledge of the patient's health status, particularly the immune system, and on metabolomics, the closest indicator of the disease phenotype. Specifically, the book provides an understanding of how metabolomics might be employed in personalized vaccinology and how the metabolic pathway of the host's system is altered by vaccine administration. Over the past few years, researchers have published articles on personalized vaccines, but these are sparse. Therefore, compiling information on this topic gives the reader an overview of the progress of the field, despite being at its infancy. Metabolomics for Personalized Vaccinology is ideally suited for researchers and postgraduate students who are interested in clinical and nonclinical studies where metabolites are used for the identification of disease and therapeutic targets.- Provides the principles of metabolomics and integration of other systems biology approach for personalized vaccine development- Discusses vaccine manufacturing technologies and importance of metabolomics for personalized vaccine development- Discusses the scope of personalized vaccine in relation to specific diseases- Possible scope of metabolomics in biomarker identification and vaccine discovery
Table of Contents
1. Personalized Vaccinology 2. Vaccine Adjuvants and their role in modulating immune signaling pathways 3. Technologies to measure vaccine immune response against infectious diseases 4. Vaccines for Cancer 5. Vaccines for Autoimmune Diseases 6. Vaccines for Allergy 7. Virus vaccine production using cell-based technology 8. Dendritic cell-based cancer vaccine production
