Spirooxindole : Chemistry, Synthesis, Characterization and Biological Significance

著者名：Patel, Gautam (EDT)/Shah, Vraj R. (EDT)/Nguyen PhD, Tuan Anh (EDT)/Deshmukh, Kalim (EDT)

Elsevier（2024/06/12発売）

• 言語：ENG
• ISBN：9780443223242
• eISBN：9780443223259

Description

Modern advances in organic synthesis require compouds having attractive properties with high percentage of yield.Spirooxindole examines the current state of the art, recent progress and new challenges associated with the development of spirooxindole derivatives for various medicinal applications. Owing to their exceptional properties, these compounds can be used in vaious fields, including chemical and pharma industries, and in clinical research.This book has chapters written by experts in several different areas. It serves as a useful reference book for scientists, industrial practitioners, graduate students, and other professionals in the field of hetrocyclic chemistry, medicinal chemistry, organic synthesis clinical research and chemical sciences.The growing interest among the academics and industrial researchers in the field of organic chemistry and medicinal chemistry is the driving force for the presentation of this edited book.- Consolidates information on each aspect of this novel compound and its applications in various fields, covering the entire spectrum of up-to-date literature citations, current market, and patents- Provides a comprehensive, in-depth description of spirooxindole derivatives as well as multipurpose scaffolds- Highlights green synthesis and nanocatalysis- Describes in-depth various medicinal applications- Covers both synthesis and applications

Table of Contents

1. Introduction of Spirooxindole 2. Synthesis of spirooxindole and its derivatives using green and nano technology 3. Stereoselective synthesis of spirooxindole scaffold 4. Characterization techniques for synthesised spirooxindole scaffold 5. Spirooxindole as a precursor 6. Medicinal applications of Spirooxindole and its derivatives- An Introduction 7. Spirooxindole derivatives as an anti-cancer agent 8. Spirooxindole derivatives as kinase based anti-cancer agents 9. Spirooxindole derivatives as an anti-viral agent 10. Spirooxindole derivatives as an anti-bacterial agent 11. Spirooxindole derivatives as an anti-oxidant agent 12. Spirooxindole derivatives as an anti-inflammatory agent 13. Other Medicinal Applications 14. A case study of the use of spirooxindole derivatives in the novel drug discovery