Description
Brody's Human Pharmacology is a well-established and much-loved textbook that guides students of medicine, pharmacology and other health professions through pharmacology from both basic and clinical perspectives.What can be a very difficult and complex topic is divided into easily digestible chapters, each of which is clearly structured from a therapeutic overview to mechanisms of action, relationships to clinical responses, pharmacokinetics, pharmacovigilance, new developments, and clinical relevance for all health professionals.- Contains all the essential aspects of pharmacology – suitable for exam preparation- Full color illustrations explain important processes and color-coded boxes enhance understanding- Therapeutic overviews, clinical problems and trade names – everything you need to know- Self-assessment questions and further reading to reinforce learning- Current developments for each class of drugs and how information relates to students in the healthcare professions bring learning to life- Updated content throughout- Pharmacodynamics chapter revised to include discussions of positive and negative allosteric modulators, as well as biased agonism- Pharmacogenetics chapter considers genetic variations and their relationship to drug responses- Section on cancer drugs revised to reflect major advances- New chapter on immunological and cell-based therapies
Table of Contents
SECTION 1 Mechanisms of Drug Action and Therapeutic Principles1. Introduction2. Cellular Receptors and Drug Concentration-Response Relationships3. Pharmacokinetics4. Pharmacogenetics5. Drug Discovery, Development, and RegulationSECTION 2 Chemical Mediators and Drugs Affecting Autonomic and Neuromuscular Synapses6. Introduction to the Autonomic Nervous SystemCholinergic Drugs7. Muscarinic Agonists, Cholinesterase Inhibitors, and Their Clinical Uses8. Muscarinic Antagonists and Their Clinical Uses9. Nicotinic Agonists and Their Clinical Uses10. Neuromuscular Blocking Drugs and Nicotinic AntagonistsAdrenergic Drugs11. Adrenergic Agonists and Their Clinical Uses12. Adrenergic Antagonists and Their Clinical UsesSECTION 3 Drug Treatment for Disorders Affecting the Central Nervous System13. The Central Nervous System14. Drug Therapy for Alzheimer Disease and Other Cognitive Disorders/Dementias15. Pharmacotherapy of Basal Ganglia Disorders: Parkinson Disease and Huntington Disease16. Drug Therapy for Psychoses and Bipolar Disorder17. Drug Therapy for Depression and Anxiety18. Drug Therapy for the Management of Attention Deficit-Hyperactivity Disorder19. Drug Therapy for Insomnia and the Hypersomnias20. Drug Therapy for Managing Obesity and Eating Disorders21. Treatment of Seizure Disorders22. Drug Therapy for Spasticity Disorders23. Ethanol, Other Alcohols, and Medications for Alcohol Use Disorder24. Psychoactive Compounds and Substance Use DisorderSECTION 4 Drug Therapy for Pain Management25. Introduction26. General Anesthetics27. Local Anesthetics28. Opioid Analgesics29. Nonsteroidal Antiinflammatory Drugs and Acetaminophen30. Cannabinoids31. Drug Therapy for Migraine HeadacheSECTION 5 Treatment of Inflammatory, Allergic and Immunologic Disorders32. Drug Therapy for Gout and Hyperuricemia33. Pharmacological Interventions for Allergic Reactions34. Immunosuppressants for Autoimmune Disorders and Organ Transplantation35. Drug Therapy for Rheumatoid ArthritisSECTION 6 Drug Treatment for Cardiovascular Diseases36. Introduction to the Regulation of Cardiovascular Function37. Overview of Hypertension Management and Drugs That Decrease Sympathetic Tone38. Diuretics and Drugs That Affect Volume and Electrolyte Content39. Drugs Affecting the Renin-Angiotensin-Aldosterone System40. Calcium-Channel Blockers41. Vasodilators for Hypertensive Crises, Pulmonary Hypertension, and Erectile Dysfunction42. Treatment of Hyperlipidemias and Atherosclerotic Cardiovascular Disease43. Treatment of Myocardial Ischemia and Angina Pectoris44. Treatment of Heart Failure45. Antiarrhythmic Drugs46. Anticoagulant, Antiplatelet, and Fibrinolytic Medications47. Drug Therapy for Hemophilia and the Deficiency AnemiasSECTION 7 Treatment of Endocrine Disorders48. Introduction to Endocrine Pharmacology49. Treatment of Hypothalamic and Pituitary Disorders50. Diagnosis and Treatment of Adrenocorticosteroid Disorders51. Female Hormone Regulation52. Androgens, Antiandrogens, and Their Clinical Uses53. Drug Therapy for the Management of Diabetes54. Drug Therapy for the Management of Thyroid Disorders55. Calcium Regulating Hormones and Other Agents Affecting BoneSECTION 8 Chemotherapy Infectious Diseases56. Principles of Antimicrobial Use57. Drugs Targeting Bacterial Cell Walls and Membranes58. Drugs Targeting Bacterial Protein Synthesis59. Drugs Targeting Bacterial DNA60. Antimycobacterial Agents61. Drugs Targeting Resistant OrganismsParasitic Diseases62. Antifungal Agents63. Antimalarial and Other Antiprotozoal Agents64. Anthelmintics and EctoparasiticidesViruses65. Antiviral Agents66. Antiretroviral Drugs for HIVCancer67. Principles of Cancer and Antineoplastic Drug Use68. Cytotoxic Agents69. Targeted Anticancer Agents70. Immunological and Cell-Based TherapiesSECTION 9 Special Considerations71. Therapeutic Use of Hematopoietic Growth Factors72. Gastrointestinal Disorders and Their Treatment73.
