Description
Respiratory critical care is essential to modern critical care medicine. To successfully support critically ill patients, an understanding of specific lung conditions and syndromes, their pathophysiological basis, and evidence-based management strategies is of vital importance. The Oxford Textbook of Respiratory Critical Care provides an authoritative account of respiratory critical care medicine with a clear focus on how to manage respiratory disease in the critically ill.The fundamentals of pathophysiology, diagnosis, and treatment, for respiratory diseases and conditions are outlined with a specific focus on management in the critical care setting. Across 66 chapters, common and unusual respiratory conditions are included as well as those aspects of pulmonary disease in which the management in critical illness is unique. The text equips the reader with up-to-date knowledge of clinical practice for the respiratory system, lung diseases within critical care medicine and the impact of critical illness on lung biology.Each chapter highlights advances in the field as well as emphasising the importance of getting the basics right. Key messages, controversies, and directions to further research points allow both focused reading and deeper engagement. A dedicated chapter to COVID-19, and sections throughout explore the impact of this novel virus in specific areas of respiratory critical care. Edited and written by an international group of recognized experts from many disciplines, this essential textbook is relevant to medics globally. This is an indispensable guide for clinicians, researchers and nurses working in Critical Care, Anaesthesia, Respiratory Medicine, Acute Medicine, and Emergency Medicine.
Table of Contents
- Part 1 Basic concepts - lung and critical care
- 1: Mark Griffiths, Mary White, and Nirmala Chakkalakal: History of Mechanical Ventilation
- 2: Richard Leach: The Respiratory System
- 3: Andrew Cumpstey and Mike Grocott: Gas Exchange
- 4: Thomas S. Wilkinson: Airway Defences
- Part 2 The Critical Care Unit
- 5: Judit Orosz and Steve McGoughlin: Organisation
- 6: Richard Keays: Emergency Planning and Disaster Management
- Part 3 Non-invasive Ventilation
- 7: Federico Longhini, Paolo Navalesi, Mariachiara Ippolito, and Cesare Gregoretti: High Flow Nasal Oxygen Therapy
- 8: Cesare Gregoretti, Andrea Cortegiani, Vincenzo Russotto, and Lara Pisani: Non invasive Ventilation in Critical Care
- 9: Federico Longhini, Rosanna Vaschetto, and Paolo Navalesi: Clinical applications of Non invasive ventilation in Critical Care
- 10: Lorenzo Ball, Francesco Tasso, Veronica Vercesi, Marco Tixi, Iacopo Firpo, and Paolo Pelosi: Medical Gases and Humidification
- Part 4 Basic Concepts in Positive Pressure Ventilation
- 11: Christoph Boesing, Thomas Luecke, and Joerg Krebs: Mechanical Ventilation: how to set up the ventilator
- 12: Pedro Leme Silva, Gary Nieman, Paolo Pelosi, and Patricia RM Rocco: Pulmonary effects of Positive Pressure Ventilation
- 13: Pedro Leme Silva, Gary Nieman, Paolo Pelosi, and Patricia RM Rocco: Extrapulmonary effects of Positive pressure Ventilation
- Part 5 Monitoring the Mechanically Ventilated Patient
- 14: Anthony Rostron, Thomas Hellyer, and A John Simpson: Monitoring airway inflammation and infection
- 15: Paolo Formenti and John J Marini: Monitoring lung protective ventilation
- 16: Benjamin Garfield and Sunil Patel: Monitoring Respiratory muscle function
- 17: Rodney A Gabriel and Michael R Pinksy: Monitoring Cardiovascular function in Critically Ill patients
- 18: Arjun Nair: Imaging Critically Ill patients
- 19: Suveer Singh: Bronchoscopy in Critical Care
- Part 6 Advanced Mechanical Ventilation
- 20: Johannes M Huitink and Lorenz G Theiler: Airway Management
- 21: Michele Umbrello, Paolo Formenti, and Davide Chiumello: Acute Respiratory Distress Syndrome
- 22: Stephan Ehrmann, Nicole P. Juffermans, Marcus J. Schultz, Nicolò Patroniti, Alex Molin, Martin Scharffenberg, Sabine Nabecker, and Marcelo Gama de Abreu: Advanced Respiratory Therapies: Inhaled therapies, Heliox, ECMO and ECCO2-R, Non conventional ventilatory modes
- Part 7 Care of the ventilated patient
- 23: Emma Louise Hartley and Andrew Retter: Thromboprophylaxis
- 24: Hollmann D. Aya and Maurizio Cecconi: Fluid Balance
- 25: Yahya Shehabi and Maja M. Green: Sedation, Analgesia, and Paralysis
- 26: Danielle E Bear and Zudin Puthucheary: Nutrition
- 27: Mette Krag, Morten Hylander Møller, Suveer Singh, and Matt P Wise: Gastric Protection
- 28: Susannah Leaver and Jonathan Ball: Mucus and Bronchopulmonary clearance
- 29: Ahmed Al-Hindawi, Eli Rogers, and Marcela P. Vizcaychipi: Delirium and Sleep
- 30: Bronwen Connolly and Paul Twose: Physiotherapy
- 31: Christopher D Hingston: Human Factors and End of Life
- Part 8 Respiratory Infections
- 32: Vimal Grover and Suveer Singh: Ventilator associated pneumonia
- 33: David R. Woods and Ricardo J. José: Bacterial Pneumonia
- 34: Jordi Rello, Eleonora Bunsow, and Leonel Lagunes: Viral Pneumonias
- 35: Jonathon P. Fanning, Gianluigi Li Bassi, Patricia Rieken Macedo Rocco, Lorenzo Ball, Antonio Messina, Marlies Ostermann, Matteo Bassetti, and Daniele Roberto Giacobbe: COVID-19 in the intensive care unit: Epidemiology, Pathophysiology, Respiratory management, Haemodynamic support, Renal support, Pharmacological treatments and Superinfection
- 36: Loïc Lang-Lazdunski: Pleural infection
- 37: Matteo Bassetti, Alessia Carnelutti, and Elda Righi: Fungal respiratory Infections
- 38: Christopher M. Orton, Hannah Jarvis, and Onn Min Kon: Mycobacterial Infections
- 39: Dhruva Chaudhry, Pawan Kumar Singh, and Manjunath B. Govindagoudar: Traveller's Pneumonia
- 40: Vanya Gant, and Cabeza Brason: Microbiology and Infectious Diseases Consultant Barts Health NHS Trust, London, UK
- Part 9 Critical Care management of Pulmonary Diseases and other Respiratory manifestations
- 41: Andrea Carsetti and Simone Bazzurro: Chronic obstructive pulmonary disease
- 42: Mara Ricci, Giovanni Carmine Iovino, Lucrezia Mincione, Ivan Dell'atti, and Salvatore Maurizio Maggiore: Asthma
- 43: Caroline Patterson and Derek Bell: Thromboembolic disease
- 44: Vasilis Kouranos: Pulmonary Haemorrhage
- 45: Laura C Price, S John Wort, and Simon J Finney: Pulmonary Hypertension and Cor Pulmonale
- 46: Peter M George, Suveer Singh, and Felix Chua: Organising Pneumonia
- 47: Philip Molyneux and Athol U Wells: Interstitial Lung disease
- 48: Nilima Parry-Jones, Jack Parry-Jones, and Matt P Wise: The Haematological patient
- 49: Hemang Yadav, Alastair C Carr, and Philippe R Bauer: Oncological aspects of respiratory critical care
- 50: Muriel Fartoukh, Guillaume Voiriot, Aude Gibelin, Julien Lopinto, Armand Mekontso-Dessap: Sickle cell disease
- 51: Michael I Polkey: Neuromuscular disease
- 52: Fraser Brims and Edward TH Fysh: Pleural Disease
- 53: Thomas Kiss and Marcelo Gama de Abreu: Chest wall disease and Post thoracic surgery
- 54: Audrey de Jong and Samir Jaber: Obesity
- 55: Timothy Scott and Christopher M R Satur: Trauma
- 56: Giorgio della Rocca and Luigi Vetrugno: Pneumothorax and Air Leaks
- 57: Timothy Crozier: The Obstetric patient
- 58: Markus Honickel, Oliver Grottke, and Rolf Rossaint: Transfusion
- 59: Jasmeet Soar, Fiona Moghaddas, and Stephen M. Robinson: Anaphylaxis
- 60: Simone Bazurro, Andrea Carsetti, and Greg McAnulty: Aspiration and Drowning
- 61: Sabri Soussi, Matthieu Legrand, and Suveer Singh: Burns and Inhalation Injury
- 62: Omender Singh, Suneel Kumar Garg, and Deven Juneja: Poisoning
- 63: Thomas Bein and Michael Pfeifer: Lung Transplantation
- Part 10 Weaning and Long-term ventilation
- 64: Patrick B Murphy, Andrew Jones, and Luigi Camporota: Liberation from Mechanical Ventilation
- 65: Rachel d'Oliveiro and Michael Davies: Home Mechanical Ventilation



