Description
Advanced Drug Delivery Systems for Colonic Disorders present the current state of the art methods for targeted drug delivery to the colon. These methods can prolong drug half-lives, improve bioavailability, optimize pharmacokinetics, and reduce medication dosing frequency.Chapters are written in a way that allows the audience to not only become familiar with the most recent advancement in the field, but to better understand them by referring to various illustrations, figures, and informative tables. The contents cover an overview of colonic diseases, the cellular and molecular mechanisms involved, current and traditional therapeutic approaches, biomaterials, oral drug delivery methods, targeted drug delivery, nutraceuticals and herbal medicine approaches, prebiotics, probiotics and symbiotics, nanomedicine approaches, and the current status of clinical trials in the area.Advanced Drug Delivery Systems for Colonic Disorders is the perfect resources for researchers in pharma, biomaterials, and nutrition to familiarize themselves with new and upcoming therapeutic methods. Research physicians in GI can also benefit from reading this book for its clinical applications. - Covers recent perspectives and challenges towards the treatment of colonic disorders- Provides insights into how advanced drug delivery systems can be effectively used for the management of various types of colonic disorders- Discusses drug delivery strategies to manage inflammatory bowel disease (chronic inflammation in the digestive tract), ulcerative colitis (inflammation and ulcers in colon), Crohn's disease, Colonic polyps, Shigellosis, Colon Bleeding or Hemorrhage, Diverticulosis and colon cancer
Table of Contents
1. Introduction to colonic disordersManvi Singh, Puru Goel, Mayank Phagna, Reena Badhwar, Zeenat Iqbal and Mohd. Aamir Mirza 2. Cellular and molecular mechanisms involved in colonic disordersSimranjit Kaur, Arshdeep Singh, Harpreet Kaur, Jagbir Singh and Rajbir Bhatti 3. Current approaches for treatment of colonic disorderManish Gupta, Priya Sen, Mahendra Saini, Mahaveer Singh, Pawan Bagiyal, Pramod Kumar andGaurav Gupta 4. Polysaccharides based drug delivery systems for the treatment of colon diseasesSadaf Arfi, Nimisha Srivastava and Deepti Dwivedi 5. Synthetic polymers as biomaterials for the treatment of colon diseasesSundeep Chaurasia and Brahmeshwar Mishra 6. Mucoadhesive polymers as biomaterials for the treatment of colon disordersNitesh Kumar, Priyanka Verma, Varun Kumar, Rachel Kaul and Surbhi Mishra 7. Colon-responsive oral drug delivery for combating colonic disordersAnindita Behera8. Colon-responsive targeted drug delivery for treating colonic disorderAnil K. Philip, Bassim I. Mohammad and Hayder A. Al-Aubaidy 9. Advancement in targeted drug delivery systems in managing colonic disordersC. Sarath Chandran, Krishnameera Sajayan, Jeeva C. Soman, P.K. Anjana, K.K. Swathy, A.S. Vishnu and Shijina Kappally 10. Nutraceuticals and phytoceuticals in the treatment of colonic disordersNitin Verma, Jatin Kumar, Neha Kanojia, Komal Thapa and Kamal Dua 11. Role of Prebiotics, Probiotics and synbiotics in the management of colonic disordersFaizan Naeem Razali, Wuen Yew Teoh, Muhammad Zaki Ramli, Ching-Yee Loo and Charles Gnanaraj 12. Era of biotics in managing colonic disordersShvetank Bhatt, K. Anitha, Sujit Kumar Sah, Nishant Prasad Apte, Sakina. Mullamitha andJamila Chechatwala 13. Innovations in liposomal drug delivery: paving the way for personalized cancer therapyAlaa A.A. Aljabali, Mohammad A. Obeid, Mohamed El-Tanani and Murtaza M. Tambuwala 14. Nanoparticulate drug delivery systems for colonic disordersGirish Kumar, Tarun Virmani, Ashwani Sharma, Reshu Virmani and Kamla Pathak15. 3D printing-assisted colon-targeted drug delivery systemsChandrakantsing Pardeshi, Ganesh Shevalkar, Mahesh Umbarkar, Dipak Bari, Kamalesh Mali,Sameer Lakade and Monica Garcıa 16. Radiopharmaceutical-based approaches for the determination of colon-targetingefficiencyAkshita Arora, Anshul Sharma, Richa Kumari and Nitin Sharma 17. Colonic disorder management: challenges an prospectsAlan Raj, M. Sonal Sekhar and Angel Treasa Alex 18. Clinical trials and regulatory aspects of drug delivery system for colonic disordersRiya Shivgotra, Manjot Kaur, Shubham Thakur, Bindu Soni, Hossamaldeen Bakrey and Subheet Kumar Jain
