Description
This book introduces transdermal drug delivery and the developments that have taken place in various transdermal drug delivery techniques including the system-level design approach of a novel miniaturized medical device to offer precise and painless drug delivery via a skin-based transdermal route. It discusses the microelectromechanical systems (MEMS)-based fabrication technique and the design, fabrication and characterization of different MEMS-based components like microneedles and micropumps. It further includes a MEMS-based component micropump with design, analysis, fabrication and characterization of the transdermal drug delivery device and challenges encountered in the design improvements.
Features:
- Summarizes transdermal drug delivery systems especially with a focus on MEMS and microneedles, including theoretical concepts
- Emphasizes system integration by describing simulation and design techniques as well as experimental fabrication
- Discusses system-level integration for miniaturized therapeutic devices
- Includes working simulation models covering microneedles and micropump analysis
- Explores future direction in development of pertinent devices
The book is aimed at researchers, professionals, and graduate students in biomedical engineering, microelectronics, micro-electro-mechanical-systems, and drug delivery.
Table of Contents
1 Transdermal Drug Delivery Systems. 2 At the bottom 窶� Microfluidics and Scaling Laws. 3 Microneedles 窶� New tools of painless interface to skin. 4 Miniaturization using microfabrication techniques. 5 Design and simulation of microneedles. 6 Fabrication and characterization of hollow Polymer microneedles. 7 C-MEMS process-based post fabrication and strength enhancement of microneedles. 8 Micropumps for drug delivery. 9 Piezoelectric Actuator-based Micropumps. 10 Ionic Polymer Metal Composite Actuators for micropumps. 11 Microneedle and IPMC micropump integrated drug delivery system
