Description
Cannabis Use, Neurobiology, Psychology, and Treatment offers readers a comprehensive reference on neurological changes, both transient and long-term, and other factors surrounding the use of these compounds and extracts. With coverage of both natural and synthetic cannabinoids, this broad coverage allows readers to learn about both adverse and non-adverse effects, including reactivity to pain, changes in behavior, and neuroactivity. This volume provides a platform for research on the effects of these compounds in brain function and neurological dysfunction. Extracts from the Cannabis sativa plant contain scores of psychoactive compounds in addition to the principal agent tetrahydrocannabinol, many of which are neuroactive.- Summarizes cannabis and cannabinoid research in relation to neurological function- Contains chapter abstracts, key facts, a dictionary and a summary- Covers the neuroactivity of multiple Cannabis compounds beyond tetrahydrocannabinol- Includes conditions like depression, anxiety, Parkinson's, psychosis, and epilepsy- Discusses brain structure and brain development, including functional connectivity
Table of Contents
PrefaceI. Setting the scene and introductory chapters1. Metabolomics of the cannabis plant Mickel Hiebert-Giesbrecht, Claudia Torres-Calzada and David Scott Wishart2. The roots of Cannabis sativa: chemical and pharmacological profile L A. Rolim3. Cannabis related compounds in beverages and food Ilaria Di Marco Pisciottano4. The impact of prenatal cannabis exposure: an overview Natalia Kleinhans5. Cannabis Genotoxicity and Cancer Incidence: Highly Concordant Synthesis of European and USA Datasets Albert Stuart Reece and Gary K. Hulse6. Cannabis Genotoxicity and Cancer Incidence: A Highly Concordant Synthesis of European and USA Datasets Albert Stuart Reece and Gary K. Hulse7. Cannabis, Cognitive impairment and Car Crash risk U.W. PreussII. Cannabis usage8. Recreational cannabis use: a French perspective of adverse effects Emilie Bouquet, Emilie Jouanjus and Maryse Lapeyre-Mestre9. Acute and chronic impact of cannabis on human cognition Justin Matheson and Bernard Le Foll10. Polydrug users, use of cannabidiol (CBD) and abuse potential/Polydrug users, use of cannabinoids and abuse potential Kerri Alexandra Schoedel11. Cannabis stigmas: a narrative of features Matt Reid12. Alterations of THC and CBD ratios and impact on cognition Erica Zamberletti13. When cannabis is used for medicinal purposes: a focus on back pain R. L. Price IIIIII. Pharmacological and Physiological Aspects14. Cannabis, cannabinoids and receptor responses Yi Yang, Roya Derwish and Lakshmi P. Kotra15. Cannabidiol (CBD): abuse potential and withdrawal Kenneth W. Sommerville and Beatrice Setnik16. 4,5- Dihydro-1H-pyrazole/3,4-Diarylpyrazoline class of cannabinoid-1 (CB1R) receptor antagonists and their potential in medicinal applications Malliga R. IyerIV. Neurobiology of cannabis17. Neurobiology of cannabis Rohit Goyal and Deepak Kumar18. The kynurenine pathway, neurobiology and cannabis misuse: a new narrative Nuria Morales-Puerto and Esther O'Shea19. Central nervous system cancers and use of cannabis and related products: an updated narrative J. Eduardo Rodriguez Almaraz and Nicholas Butowski20. Chronic cannabis users: links with glutamate and resting state connectivity S.D. Newman21. Brain metabolic responses to cannabis use in people with multiple sclerosis: Insights from [18F]-FDG positron emission tomography and functional MRI Thorsten Rudroff22. Genetic Variation and Acute Responses to Cannabis Bernard Le Foll, Zoe Bourgault and Justin Matheson23. Cell Signaling of the CB1 Cannabinoid Receptor via beta-arrestins, Cannabinoid Receptor Interacting Protein (CRIP1a) and other regulatory proteins Allyn C. Howlett24. Cannabis and impact on memory: from in utero to adults Jennifer Willford, Meaghan Hazelet, Mohamad Khalaifa, Natacha DeGenna and Gale A. Richardson25. Central CB1 receptors and age-related changes: investigating the effects of DELTA-9-tetrahydrocannabinol Brett C. Ginsburg and Hanana AlTfaili26. Alcohol, cannabis and visual memory Concepcion Vinader-CaerolsV. Neurobiology of cannabinoids27. The role of Delta-FosB in the plasticity of the cannabinoid system Arturo Venebra-Munoz and Sara Mejía-Chávez28. Functional profile of synthetic cannabinoid receptor agonists: exploring cannabinoid and non-cannabinoid targets Shivani Sachdev, Marina Santiago and Chris Bladen29. Linking the G protein-coupled orphan receptor GPR55 to the cannabinoid receptors (CB1 and CB2): a new narrative Paula Morales, Raquel Guerrero-Alba and B.A. Marichal-Cancino30. Proteomic analysis of cannabinoids in human oligodendrocytes Valéria Almeida31. Cannabinoids and endocannabinoid signaling at the basal forebrain cholinergic system Rafael Rodriguez32. Cannabidiol (The major non-psychotropic cannabinoid in the cannabis plant) and the PI3K/Akt pathway in the CNS Nadja Schroder33. Effects of cannabidiol and other phytocannabinoids on ion channels Murat Oz, Keun-Hang Susan Yang, Mohamed Mahgoub, Georg Petroianu and Dietrich Lorke34.
