Description
A current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction is detailed in our Neurobiology of Addiction series, each volume addressing a specific area of addiction. Opioids, Volume 4 in the series, explores the molecular, cellular and systems in the brain responsible for opioid addiction using the heuristic three-stage cycle framework of binge/intoxication, withdrawal/negative affect, and preoccupation/anticipation.- Highlights recent advances in opioid addiction- Includes Neurocircuitry, Cellular and Molecular neurobiological mechanisms of opioid addiction- Defines opioid abuse and addiction potential, including biological tolerance
Table of Contents
1. Definitions2. History of opioid use3. Mechanism of action: endogenous opioid system4. Physiological effects5. Behavioral effects6. Pharmacokinetics7. Behavioral mechanism of action8. Medical use, abuse, and addiction9. Neurobiological effects10. Summary
