Description
Tailor-Made Polysaccharides in Drug Delivery provides extensive details on all the vital precepts, basics and fundamental aspects of tailored polysaccharides in the pharmaceutical and biotechnological industry for understanding and developing high quality products. The book offers a comprehensive resource to understand the potential of the materials in forming new drug delivery methods. It will be useful to pharmaceutical scientists, chemical engineers, and regulatory scientists and students actively involved in pharmaceutical product and process development of tailored-made polysaccharides in drug delivery applications.The utilization of natural polymeric excipients in numerous healthcare applications demand the replacement of the synthetic polymers with the natural ones due to their biocompatibility, biodegradability, economic extraction and readily availability. The reality behind the rise in importance of these natural materials is that these sources are renewable if grown in a sustainable means and they can tender incessant supply of raw materials. Amongst these natural polymers, polysaccharides are considered as excellent excipients because of its non-toxic, stable, biodegradable properties. Several research innovations have been made on applications of polysaccharides in drug delivery.- Provides methodologies for the design, development and selection of tailor-made, natural polysaccharides in drug delivery for particular therapeutic applications- Includes illustrations that demonstrate the mechanism of biological interaction of tailor-made polysaccharides- Discusses the regulatory aspects and demonstrates the clinical efficacy of tailor-made polysaccharides
Table of Contents
1. Synthesis of tailor-made polysaccharides: An overview2. Drug delivery dosage forms made of tailor-made natural polysaccharides3. Carboxymethylated polysaccharides in drug delivery4. Thiolated polysaccharides in drug delivery5. Cross-linked polysaccharides in drug delivery6. Graft copolymers of polysaccharides: Synthesis techniques and pharmaceutical applications7. Grafted polysaccharides in drug delivery8. Polysaccharide-based polyelectrolyte complex systems in drug delivery9. Polysaccharide-based interpenetrating polymeric network systems in drug delivery10. Polysaccharide nanoconjugates in drug delivery11. Functionalized chitosan in drug delivery 12. Modified alginates in drug delivery13. Uses of tailor-made plant starches in drug delivery14. Cancer targeting by tailor-made polysaccharides15. Delivery of gene and growth factors using tailor-made polysaccharides
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