Description
Stem Cells and COVID-19 presents up-to-date knowledge on the effect of hematopoietic and mesenchymal stem cells to combat SARS-CoV-2 infection in its diagnosis, treatment and prevention. In addition, the book critically discusses challenges, highlighting outstanding questions and future perspectives. Written by global experts in the field for both pre-clinical and clinical practitioners, this comprehensive book delves into how stem cells have a strong potential in developing better diagnostic, treatment and preventive strategies in SARS-CoV-2 infection.Both hematopoietic and mesenchymal stem cells are critical to better understand the response of immune system to coronavirus infection in both healthy and co-morbid conditions in the development of effective vaccines and immunotherapies.- Focuses on diagnosis, treatment and prevention- Presents different aspects to enable researchers in the field to move toward designing novel therapeutics in the treatment of COVID-19- Provides coverage of challenges and future perspectives in this fast-moving field
Table of Contents
1. Introduction2. Characteristics and Immunobiology of COVID193. Molecular Mechanism and translation approaches4. Inflammatory multisystem syndrome in COVID19: Insights on off-target organ system in susceptible and recovering population5. Cytokine storm and stem cell activation in unveiling potential targets for diagnosis and therapy6. Mesenchymal and hematopoietic stem cells: Novel avenues in combating COVID197. Immunomodulatory properties of mesenchymal and hematopoietic stem cells – potential therapeutic target for COVID-198. COVID19 and acute myocardial injury: Stem cell driven tissue remodeling in COVID19 infection9. Stem cell born signals and tissue regeneration in COVID19 infection10. Stem cell transplantation COVID19 management: Translational possibilities and future11. Therapeutic scale stem cell-derived exosomes for COVID - 19: Models – Validation, Management & Strategies12. Therapy: present & future clinical perspective
