Description
Atopic dermatitis (eczema) is one of the most common and most challenging skin conditions, for patients and practitioners alike. Uniquely organized by intrinsic and extrinsic etiologies, Atopic Dermatitis: Inside Out or Outside In? examines a myriad of causes that start from both the inside of the body and from the external environment, offering physicians practical ways to design treatments that specifically address these causes. Drs. Lawrence S. Chan and Vivian Y. Shi, along with a team of expert contributing authors, examine the etiology of this complex disorder and provide targeted, comprehensive solutions and the most useful therapeutic plans based on pathophysiology, including evidence-based integrative management.- Analyzes the pathophysiology of atopic dermatitis from two distinct fronts: inside out and outside in—an approach that is unique in the field.- Begins with an overview of the disease, then delves into both internal and external pathogenic factors, followed by the Clinician's Corner, which offers practical recommendations for treatment.- Organizes therapeutic discussions by corresponding pathophysiology rather than a one-size-fits-all approach.- Covers recently FDA-approved and emerging medications, as well as atopic comorbidities.
Table of Contents
Section I: A History of Atopy1 Historic Perspective2 Atopy Redefined3 Atopy of the Skin4 EpidemiologySection II: External Factors5 Skin Barrier6 Skin and Gut Microbiome7 Immunogens 8 Nutrition9 Oxidative Stress, Environmental factors, Pollutants10 Clinical Evidence: External FactorsSection III: Internal Factors11 Keratinocytes12 Microvasculature13 Humoral Factors14 Cellular Factors15 Skin-Gut-Lung Epithelial Permeability 16 Neurosensory Mechanisms 17 Epigenetics18 Clinical Evidence: Internal FactorsSection IV: Clinician's Corner19 Therapeutic Guideline Overview20 Topical Therapies21 Wound care22 Skin barrier Repair 23 Emerging Targeted Treatments24 Microbiome Modulation25 Itch and Pain Treatments26 Complementary and Alternative Approaches 1 27 Complementary and Alternative Approaches 2
