Description
Ion channels generate bioelectricity. Recent findings have documented the biophysical properties, the structure, assembly and regulation, and function and dysfunction of nonclassical nervous system ion channels. This book reviews nonclassical ion channel research, ranging from the basic biology, structure, regulations to their functions not only in normal physiology but also neurological disorders, using a variety of cutting-edge techniques and novel animal models.
Table of Contents
Preface
Editors
Contributors
1. Endogenous Activation and Neurophysiological Functions of Acid-Sensing Ion Channels
Wei-Zheng Zeng, Yi-Zhi Wang, and Tian-Le Xu
2. Acid-Sensing Ion Channels and Synaptic Plasticity: A Revisit
Ming-Gang Liu, Michael X. Zhu, and Tian-Le Xu
3. Trimeric Scaffold Ligand-Gated Ion Channels
Xiao-Na Yang, Si-Yu Wang, Jin Wang, and Ye Yu
4. Eukaryotic Mechanosensitive Ion Channels
Wei-Zheng Zeng and Bailong Xiao
5. Ion Channels in Human Pluripotent Stem Cells and Their Neural Derivatives
Ritika Raghavan, Robert Juniewicz, Maharaib Syed, Michael Lin, and Peng Jiang
6. Exocytosis of Nonclassical Neurotransmitters
Xiao Su, Vincent R. Mirabella, Kenneth G. Paradiso, and Zhiping P. Pang
7. Nonclassical Ion Channels in Learning and Memory
Ze-Jie Lin, Xue Gu, Tian-Le Xu, and Wei-Guang Li
8. Neuropeptide Regulation of Ion Channels and Food Intake
Xiaobing Zhang
9. Prefrontal Inhibitory Signaling in the Control of Social Behaviors
Qian Yang, Jun Wang, and Han Xu
10. Studying Brain Function Using Non-human Primate Models
Neng Gong
11. Application of In Vivo Ca2+ Imaging in the Pathological Study of Autism Spectrum Disorders
Pan Xu, Yuanlei Yue, and Hui Lu
12. Nonclassical Ion Channels in Depression
Zahra Farzinpour and Zhi Zhang
13. Ion Channels of Reward Pathway in Drug Abuse
Wen Zhang
14. Ion Channel Conformational Coupling in Ischemic Neuronal Death
Yi-Zhi Wang and Michael X. Zhu
15. Nonclassical Ion Channels and Ischemia
Jun Gao and Hui-Xin Zhang
16. Transient Receptor Potential Channels and Itch
Mahar Fatima, Jingyi Liu, and Bo Duan
17. Two-Pore Domain Potassium Channels in Pain and Depression
Shaoying Zhang and Huaiyu Yang
18. Lysosomal Ion Channels and Human Diseases
Peng Huang, Mengnan Xu, Yi Wu, and Xian-Ping Dong
19. Microglial Voltage-Gated Proton Channel Hv1 in Neurological Disorders
Madhuvika Murugan and Long-Jun Wu
Index
