Mitochondrial Physiology and Vegetal Molecules : Therapeutic Potential of Natural Compounds on Mitochondrial Health

著者名：Oliveira PhD, Marcos Roberto de (EDT)

Academic Press（2021/07/14発売）

• 言語：ENG
• ISBN：9780128215623
• eISBN：9780128215838

Description

Mitochondrial Physiology and Vegetal Molecules: Therapeutic potential of natural compounds on mitochondrial health provides a comprehensive overview of mitochondrial physiology throughout the human life span, as well as the effect of molecules of vegetal origin on mitochondrial health. The editor has lined up a team of worldwide experts to cover the most exciting and high-impact advancements of research in this area.This book is structured into two parts that provide a balance of both foundational and applied content. Part I provides an overview of mitochondrial physiology including its structure, dynamics, biogenesis, membranes, DNA transcription, and translation in the mitochondria. Part I also covers other themes such as apoptosis. Part II then covers the effect of specific vegetable-derived molecules on mitochondrial health, including anthocyanins, caffeine, cannabinoids, carnosic and rosmarinic acids, citrus flavonoids, polyphenols, pterostilbene, resveratrol, and sulforaphane, among others.Mitochondrial Physiology and Vegetal Molecules: Therapeutic potential of natural compounds on mitochondrial health is a complete resource for researchers in this exciting field. Its comprehensive coverage makes it particularly interesting to bioscience researchers willing to understand the foundations of mitochondrial physiology throughout the human life span. Clinician researchers, MDs, nutritionists, pharmacologists, and sports scientists may be attracted to the detailed information on the health effects of vegetal origin molecules on the organelle.- Contains detailed information on plant products and their effect on mitochondria- Proposes therapies and reviews mechanisms of absorption at the cellular level- Discusses the limited bioavailability of plant molecules/compounds in the human organism- Includes coverage of specific conditions such as Sports and affective disorders, among others- Presents the protective effects of plant products in mitochondrial health through all stages of life

Table of Contents

Part I - Overview of Mitochondrial Physiology1. Mitochondria: Ultrastructure, Dynamics, Biogenesis and Main Functions2. Mitochondrial biogenesis and mitophagy3. DNA transcription and translation in the mitochondria4. Mitochondrial redox biology: reactive species production and antioxidant defenses5. Mitochondria and apoptosis6. Mitochondria-Associated Membranes in the Maintenance of Cell HomeostasisPart II - The effects of plant molecules on the mitochondria in health and disease7. Biopharmaceutical Properties of Natural Products8. Carnosic acid and brain mitochondria9. Rosmarinic acid and the mitochondria10. The effects of sulforaphane on the mitochondria11. Cannabinoids and mitochondria12. Anthocyanins, effects in mitochondria and metabolism13. Preclinical evidence of the therapeutic role of pterostilbene: focus on the mitochondria14. Polyphenols attenuate mitochondrial dysfunction induced by amyloid peptides15. Plant molecules to treat eye mitochondria16. Mitochondria as a target for monoterpenes17. Baccharis trimera phytochemicals and the mitochondria18. Citrus flavonoids and the mitochondria19. Caffeine and the brain mitochondria20. Curcumin and the mitochondria21. Catechins, neuroprotection and brain mitochondria22. The effects of catechins on the cardiac mitochondria23. Possible Roles of Garlic and Its Bioactive Components on Mitochondrial Function in Physiological and Pathological Conditions24. Resveratrol effects on skeletal muscle mitochondria and contractile function25. Antiaging effects of natural agents in the skin: focus on the mitochondria26. Role of quercetin in the glial mitochondria: Implications for health and disease27. The Therapeutic Effects of Lycopene on Mitochondrial Function in Human Diseases28. Ascorbic acid and the mitochondria29. Soy isoflavones, mitochondria, and cell fate30. Resveratrol and the brain mitochondria31. The role of plant molecules on the prevention and treatment of mitochondriarelated intoxication32. Mitochondrial toxicity induced by plant molecules33. Mitohormesis