Description
Toxicology: Oxidative Stress and Dietary Antioxidants examines the nature of oxidative stress as a consequence of exposure to toxins and how antioxidant approaches can mitigate the impact of toxicant exposures. Sections covers the basic biology of oxidative stress, from molecular biology, to physiological pathology, mechanisms of action of specific toxicants, metals and other chemicals/drugs, and antioxidant approaches and therapies for toxic exposures. With contributions from an international group of experts, useful summary sections, a dictionary of terms, and applications to other areas of toxicology, this book is an informative, consolidated reference that helps bridge the interrelationship between toxicology, oxidative stress and antioxidants.- Provides a novel collection of information linking both sides of redox biology (oxidants and antioxidants) and toxicology- Explores the role of free radical mediated damage and toxicology- Contains contributions from experts on toxicological science surrounding oxidative stress and on antioxidant approaches for reducing the impact of toxicant exposures
Table of Contents
PART 1 TOXICOLOGY AND OXIDATIVE STRESSAGRICULTURAL AND INDUSTRIAL CHEMICALS1. Organophosphate pesticides toxicity, liver cells and linking oxidative stress2. Organophosphate insecticide toxicity and linking oxidative stress3. Organochlorine pesticide toxicity and linking oxidative stress4. Paraquat and reactive oxygen species damage5. Atrazine and oxidative stress6. Fungicide and oxidative stress: a focus on Ziram7. Dioxins and oxidative stress8. Polyaromatic hydrocarbons9. Oxidative stress and neonicotinoid insecticidesMETALS10. Lead toxicity and linking oxidative stress11. Cadmium toxicity and linking oxidative stress (author to link in human aspects)12. Mercury toxicity and linking oxidative stress as indicated by malondialdehyde13. Chromium toxicity and linking oxidative stress14. Arsenic toxicity and linking oxidative damage15. Rare earth element toxicity and genes in linking oxidative stress pathwaysDRUGS, FOOD DERIVED, CHEMICALS AND OTHER AGENTS16. Asbestos fibers and oxidative stress17. Anticancer agents and apoptotic cell death: linking antioxidant genes18. Chlorine toxicity, oxidative stress and impact on isoprostanes19. Ionic liquids as toxic agents and effects reactive oxygen species20. 1,2-Dichloropropanetoxicity and reactive oxygen species21. Aflatoxin B1 toxicity and the role of oxidative stress22. Acetaminophen toxicity: the role of free radical mediated injury23. Alcohol toxicity and the role of oxidative stress24. Air pollution and pulmonary oxidative stress25. Radiation and oxidative stress26. Statins and oxidative stress with statinsPART 2 ANTIOXIDANTS AND TOXICOLOGYAGRICULTURAL AND INDUSTRIAL CHEMICALS27. An overview of antioxidants28. Garlic extract and protection in malathion induced damage: facets of oxidative stress29. Laurocerasus officinalis roem. (cherry laurel) fruit and protection against organophosphate insecticides30. Resveratrol and protection in malathion-induced oxidative stressMETALS31. Vitamin C and protection against arsenic32. Fragaria ananassa and protection against cadmium toxicity33. Citicoline as a nutraceutical and protection in metal poisoning34. Acai fruit (Euterpe oleracea) and protection in mercury related oxidative stress35. Antioxidant N-acetyl-l-cysteine in chromium protection36. Nigella sativa seeds in lead related oxidative stress37. Catechin and protection in cadmium toxicity38. Kolaviron (KV) as an antioxidant: modelling arsenite toxicityDRUGS, FOOD DERIVED, CHEMICALS AND OTHER AGENTS39. Moringa oleifera leaf extract and acetaminophen protection40. All-trans-retinoic acid and protection against renal toxicant p-aminophenol41. Rhus tripartita extracts and ethanol-induced toxicity: glutathione-S-transferases and beyondGENERAL ASPECTS 42. Antioxidants in Cynara scolymus and applications to toxicological sciences43. Antioxidants in Crataegus Monogyna L flowers and applications to toxicological sciences44. Nutrient based RiduROS and use in oxidant stress protection in radiation45. Vernonia amygdalina (Del.) as an antioxidant in toxic injury
