胃不全麻痺 Gastroparesis : Pathophysiology, Clinical Presentation, Diagnosis and Treatment

著者名：Mccallum, Richard (EDT)/Parkman, Henry (EDT)/Clarke, John (EDT)/Kuo, Braden (EDT)

Academic Press（2020/09/30発売）

• 言語：ENG
• ISBN：9780128185865
• eISBN：9780128185872

Description

Gastroparesis: Pathophysiology, Clinical Presentation, Diagnosis and Treatment is a reference book providing a centralized source of data on gastroparesis collected over the last decade. Contents include the pathophysiology, clinical presentation, diagnostic recommendations and treatment options for gastroparesis. The reference is split into broad subsections, with the strategy of first focusing on the key features of the disease and then turning to controversies, recent developments, patient support resources, the spectrum of treatment – including medical and surgical - and future directions.Chapters will include coverage of important topics like autonomic neuropathy, the brain-gut axis, potential pathophysiological advances at the cellular level, diagnostic and therapeutic options specifically targeted at the pylorus, and the evaluation of the female predominance in gastroparesis. This is a must-have resource for scientists looking to find the next step in their research as well as healthcare professionals ranging from Gastroenterologists to Internists, Surgeons, Nutritionists, Psychiatrists, and Psychologists, Residents and Medical Students who struggle with how to optimally take care of their gastroparetic patients.- Provides a comprehensive overview of what is known regarding the pathophysiology, clinical presentation, diagnostic considerations and treatment options for gastroparesis- Includes key updates made in the last decade, including the progress made by the NIH Gastroparesis Consortium- Presents both sides of key controversies in the field, including the debate between classification of gastroparesis versus functional dyspepsia- Fully reviews the major advances in pharmacologic agents for therapy, both anti-emetics and prokinetics- Extensive update on the "Pyloric Revolution" and our understanding of the pathophysiology of gastroparesis and how the focus on the pylorus has literally transformed our treatment strategy with an emphasis on both surgical and endoscopic advances in addressing pyloric dysfunction

Table of Contents

I. Introduction & clinical presentation1. Historical perspectives on gastric motility and gastroparesis2. Epidemiology of gastroparesis3. Clinical presentations of gastroparesis4. Natural history of patients with gastroparesisII. Pathophysiology5. Gastric dysmotility at the organ level in gastroparesis6. Cellular pathogenesis of gastroparesis7. Sensory dysfunction in gastroparesis8. Pathology of gastroparesis: ICC, enteric neurons and fibrosis9. Gastroparesis and the brain-gut axis10. Autonomic neuropathies and gastroparesisIII. Diagnostic considerations11. Gastric emptying scintigraphy12. The use of wireless motility capsule in the diagnosis and monitoring of gastroparesis13. Breath tests for the assessment of gastroparesis14. Magnetic resonance imaging for gastric motility and function15. Electrogastrography for suspected gastroparesis16. Antroduodenal manometry for the evaluation of patients with suspected gastroparesis17. Ancillary testing including barostat, SPECT, and satiety testingIV. Clinical subsets18. Diabetic gastroparesis19. Postsurgical gastroparesis20. Idiopathic gastroparesis21. Gastroparesis from other causes22. Pediatric gastroparesisV. Therapeutic considerations23. Dietary therapy for gastroparesis24. Prokinetic agents for gastroparesis25. Antiemetic therapy for gastroparesis26. Abdominal pain in gastroparesis: Prevalence, potential causes and management27. Psychiatric aspects of gastroparesis28. Alternative, complementary medicine and cannabinoids for gastroparesis29. Enteric tube placement for gastroparesis: Gastrostomy, gastrojejunostomy and jejunostomy30. Gastric electrical stimulation for gastroparesis31. Surgical management of gastroparesisVI. Controversies & new developments32. Studies from the NIH Gastroparesis Clinical Research Consortium: Towards improving our understanding and treatment of gastroparesis33. Evaluating response in gastroparesis: Patient reported outcome measures and survey34. The pyloric revolution: Patient selection35. Endoscopic full-thickness gastric biopsy: Ready for prime time?36. Distinguishing between functional dyspepsia and gastroparesis: Does it matter?37. Female predominance in gastroparesis38. A brief history and future directions of permanent, temporary, and endoscopic GES39. Cell transplantation for gastroparesis40. A vision of the future for gastroparesis41. Resources for the gastroparesis patient