Description
Genetics, Neurology, Behavior, and Diet in Parkinson's Disease: The Neuroscience of Parkinson's Disease, Volume 2 provides a single source of material covering different scientific domains of neuropathology underlying this condition. The book covers a wide range of subjects and unravels the complex relationships between genetics, molecular biology, pharmaceutical chemistry, neurobiology, imaging, assessments, and treatment regimens. It fills a much-needed gap as a "one-stop" synopsis of everything to do with the neurology and neuroscience related to Parkinson's disease—from chemicals and cells to individuals. It is an invaluable resource for neuroscientists, neurologists, and anyone in the field.- Offers the most comprehensive coverage of a broad range of topics related to Parkinson's disease- Serves as a foundational collection for neuroscientists and neurologists on the biology of disease and brain dysfunction- Contains in each chapter an abstract, key facts, mini dictionary of terms, and summary points to aid in understanding- Features preclinical and clinical studies to help researchers map out key areas for research and further clinical recommendations- Serves as a "one-stop" source for everything you need to know about Parkinson's disease
Table of Contents
Part I: Genetics, molecular and cellular biology2. Alpha-synuclein gene and Parkinson's diseaseAthina-Maria Simitsi, Chistos Koros and Leonidas Stefanis3. The DJ-1 gene and protein: links with Parkinson's diseaseVanessa J. Musco, Sarah J. Annesley and Paul R. Fisher4. Regulation of tyrosine hydroxylase: relevance to Parkinson's diseaseGelareh Alam and Jason R. Richardson5. Linking glucocerebrosidase gene (GBA) variants and Parkinson's diseasectoria Berge-Seidl and Mathias Toft6. Astrocytes and microglia in Parkinson's disease and animal modelsKatarzyna Kuter7. The role of autophagy in Parkinson's disease etiopathogenesisEmanuel Candeias, Jãao Duarte Magalhães, Daniel Santos, Helena Costa, Diana F. Silva, Ana Raquel Esteves and Sandra Morais Cardoso8. The mitochondrial network in Parkinson's diseaseAndreas Aufschnaiter, Verena Kohler and Sabrina Büttner9. Signal transduction in Parkinson's disease: modulation of neurotransmission, symptomatology, and therapyMattia Volta10. Oxidative stress signaling and regulated cell death in Parkinson's diseaseCarlos Velez-Pardo and Marlene Jimenez-Del-Rio11. Subcellular-specific alpha-synuclein in Parkinson's diseaseBenjamin Rosen, Ketan S. Patil, Guido W. Alves and Simon G. Møller12. Melanocortin 1 receptor: Parkinson's disease, melanoma risk, and neuroprotectionGemma Tell-Marti, Joan Anton Puig-Butillé and Susana Puig13. Energy regulation and Parkinson's diseaseLiting Hang and Kah-Leong Lim14. Linking rotigotine, Parkinson's disease, and brain-derived neurotrophic factorKazuhiro Sohya, Kazunori O'Hashi and Hiroshi KunugiPart II: Neurology, physiology and imaging15. The different syndromes in Parkinson's disease: an overviewNikolaos Giagkou and Maria Stamelou16. Neuromolecular imaging in Parkinson's diseasePatricia A. Broderick and Leslie Wenning17. Interlinking brain mapping and Parkinson's disease: MRI analysis, nigrosome 1 and nigrosome 4Eung Yeop Kim, Young Hee Sung and Jongho Lee18. Interconnecting Parkinson's disease: the use of computed tomography and microelectrode recording in DBS surgeryRyan B. Kochanski and Sepehr Sani19. Linking diffusion tensor imaging, microstructures and Parkinson's diseaseYu Zhang, Norbert Schuff, I-Wei Wu and Duygu Tosun20. Detecting parkinsonian degeneration in lateroventral tier of substantia nigra pars compacta with MRIJason Langley, Daniel E. Huddleston and Xiaoping P. Hu21. Vagal motoneurons in Parkinson's diseaseRuth E. Musgrove, Wei-Hua Chiu and Joshua A. Goldberg22. Circadian clock disruption and neuroinflammation in Parkinson's disease: a new perspective Elisabetta Lauretti and Domenico Praticò23. Motor cortex stimulation in Parkinson's diseaseAngelo Lavano, Giusy Guzzi, Attilio Della Torre and Domenico La Torre24. Action programming disorders associated with Parkinson's diseaseKenneth M. Heilman25. The striatal medium spiny neurons: what they are and how they link with Parkinson's diseaseFu-Ming Zhou26. Disruptions of frontostriatal language functions in Parkinson's diseaseAdolfo M. García, Yamile Bocanegra, Agustina Birba, Juan Rafael Orozco-Arroyave, Lucas Sedeño and Agustín Ibañez27. Alpha-synuclein and neuroinflammation in Parkinson's diseaseTatiana Varanita and Luigi Bubacco28. Tau and its interactions with other proteins in neurodegenerative diseasesKatelyn H. Mroczek, Sarah J. Annesley and Paul R. Fisher29. Interaction between brain angiotensin and dopaminergic systems and Parkinson's diseaseJose Luis Labandeira-Garcia, Pablo Garrido-Gil, Maria A. Pedrosa, Carmen M. Labandeira and Ana I. Rodriguez-Perez30. Restoring dopamine levels in Parkinson's disease: neuronal pathways, agonists and antiinflammatory agentsÁgatha Oliveira-Giacomelli, C.M. Albino, Hellio Danny Nóbrega de Souza and Henning UlrichPart III: Behaviour and psychopathology31.
