Description
Covering all the basic and clinical concepts you need to know for your coursework and USMLEs, Immunology, 9th Edition, offers a well-illustrated, carefully structured approach to this complex and fast-changing field. Carefully edited and authored by experts in both teaching and research, it provides cutting-edge, consistent coverage that links the laboratory and clinical practice. A user-friendly, color-coded format, including key concept boxes, explanatory diagrams, and nearly 200 photos to help you visually grasp and retain challenging concepts.- Explains the building blocks of the immune system - cells, organs, and major receptor molecules - as well as initiation and actions of the immune response, especially in a clinical context.- Includes extensive updates to clinical information, including recent clinical approaches in cancer immunology, transplantation, autoimmunity, hypersensitivity, and more.- Features a reorganized format that presents immunology in the order in which is typically taught and learned, better integrating basic and clinical immunology.- Covers new topics such as innate lymphoid cells, antibody-based therapies and antibody engineering, innate immunity and its components, the genetics of immunologically-based diseases and personalized medicine, and immunotherapeutic agents for the treatment of cancer.- Provides Critical Thinking boxes, chapter-opening summaries, and case-based and USMLE-style questions that provide effective review and quick practice for exams – plus more learning opportunities online, including USMLE-style questions and clinical cases. Includes extensive updates to clinical information, including recent clinical approaches in cancer immunology, transplantation, autoimmunity, hypersensitivity, and more.Covers new topics such as innate lymphoid cells, antibody-based therapies and antibody engineering, innate immunity and its components, the genetics of immunologically-based diseases and personalized medicine, and immunotherapeutic agents for the treatment of cancer.
Table of Contents
SECTION 1 The Immune System and Innate Immunity1 Introduction to the Immune System2 Cells, Tissues and Organs of the Immune System3 Mechanisms of Innate Immunity4 Complement5 Mononuclear Phagocytes in Immune DefenceSECTION 2 Adaptive Immune Responses6 T-Cell Receptors and Major Histocompatibility Complex Molecules7 Antigen Presentation8 Cell-Mediated Cytotoxicity9 B-Cell Development and the Antibody Response10 Antibodies11 Immunological Tolerance12 Regulation of the Immune Response13 Immune Responses in TissuesSECTION 3 Defence Against Infectious Agents14 Immunity to Viruses15 Immunity to Bacteria and Fungi16 Immunity to Protozoa and Worms17 VaccinationSECTION 4 Immunodeficiency18 Primary Immunodeficiencies19 AIDS, Secondary Immunodeficiency and ImmunosuppressionSECTION 5 Immune Responses Against Tissues20 Autoimmunity and Autoimmune Disease21 Transplantation and Rejection22 Immunity to CancersSECTION 6 Hypersensitivity23 Immediate Hypersensitivity (Type I)24 Hypersensitivity (Type II)25 Hypersensitivity (Type III)26 Hypersensitivity (Type IV)
