Description
Tumor Vascularization discusses the different types of growth of tumor blood vessels and their implications on research and healthcare. The book is divided into three parts: the first one, General Mechanisms, discusses different vessel growth mechanisms, such as sprouting angiogenesis, non-angiogenesis dependent growth, intussusceptive microvascular growth, vascular co-option and vasculogenic mimicry. The second and third parts, entitled Clinical Implications and Therapeutic Implications are dedicated to translating recent findings in this field to patient treatment and healthcare. This book is a valuable source for cancer researchers, oncologists, graduate students and members of the biomedical field who are interested in tumor progression and blood vessels.- Explains new, non-orthodox concepts recently developed and related to the modality of growth of tumor blood vessels- Provides information on the types of angiogenesis, non-angiogenesis dependent growth and vascular co-option, discussing both their similarities and differences- Encompasses a discussion on clinical implications of tumor vascularization to translate research findings into treatment
Table of Contents
1. Sprouting and non-sprouting angiogenesis in tumors2. Nonangiogenic tumor growth3. Vascular co-option4. Pericyte mimicry: an embryonic-like mechanism for tumor metastasis5. Vasculogenic mimicry6. Postnatal vasculogenesis7. The perivascular niche8. Zebrafish as an experimental model to study tumor angiogenesis9. Clinical implications
