Description
Molecular Nutrition: Vitamins presents the nutritional and molecular aspects of vitamins with a specific focus on vitamins A, B1 (thiamine), B2 (riboflavin), B# (niacin), B5 (pantothenic acid), B6, (pyridoxine), B7 (biotin), B9 (folate), B12 (colbamin), C, D, E, and K. As part of the Molecular Nutrition series, this book discusses introductory aspects and general coverage of vitamins and nutrition, the molecular biology of the cell, including signaling, transporters, oxidative stress, receptors, uptake, immunity, proliferation, endoplasmic reticulum, differentiation, carcinogenesis and apoptosis. Final sections cover genetic machinery and its function, transcriptional processes, homeostasis genes, cancer, gene expression, mutations, and more.Emerging fields of molecular biology and important discoveries related to diet and nutritional health are also covered, rounding out the book.- Summarizes molecular nutrition in health as related to vitamins- Includes material on signaling, transporters, oxidative stress, receptors, uptake, immunity, proliferation, endoplasmic reticulum, differentiation, carcinogenesis and apoptosis- Presents transcriptional processes, homeostasis genes, cancer, gene expression, mutations, the sodium-dependent multivitamin transporter, p53, p21, microRNAs, one carbon metabolism, nucleic acids, DNA methylation and polymorphisms- Addresses emerging fields of molecular biology and presents important discoveries related to diet and nutritional health- Covers Vitamins A, B, C, D, E, and K- Discusses their impact on health relating to cancer, diabetes, arthritis, and aging- Includes key facts, a mini dictionary of terms, and summary points
Table of Contents
I General and Introductory Aspects1. Vitamin E: An Overview2. Requirements for Vitamins in Different Stages of the Life Cycle3. Vitamin C: Metabolism, Epigenetic Roles, and Cancer4. Riboflavin and Health: A Review5. A Review of Vitamin B12II Molecular Biology of the Cell6. Vitamin D Receptor in Arterial Ageing7. Tocotrienol Regulation of AMPK in Cancer8. Niacin and Hyperlipidemia9. Folate Transporters in Placentas10. Linking B-vitamins, Choline, and Stroke11. Riboflavin (Vitamin B2) and Mitochondrial Energy12. Pantothenic Acid (Vitamin B5) - Immunoreactive Neurons13. Ascorbic Acid (Vitamin C) and Alzheimer's Disease14. Vitamin B1 and the Pyruvate Dehydrogenase Complex15. Vitamin D and Diabetes Mellitus: Vitamin D Metabolism, Alterations of Vitamin D Endo-paracrine System and their Relation to Oxidative/Nitrosative Stress, Inflammation, and Cell survival16. Grape Seed Extract and Pyridoxine (Vitamin B6) 17. Cobalamin (Vitamin B12) Malabsorption18. Pyridoxine (Vitamin B6) and Selenium Interactions: Implications for Human Health 19. Linking Vitamin E and Nitric Oxide in Liver Disease20. Use of Methylcobalamin (Vitamin B12) in Pain21. New Properties of Vitamin B6 or Pyridoxine in Experimental Oxidative Stress in the Brain22. Thiamine (B1), Oxidative Stress, and Ethanol 23. Vitamin E: Novel Metabolites and Treatments24. Vitamin E Structure and Forms/Analytical Methods25. Pyruvate Carboxylase (PC) and the Biotin Carboxylase Domain26. Application of Vitamins27. Vitamins in Chronic Kidney Disease28. Inflammatory Bowel Disorders and Fat-soluble Vitamins29. Vitamin E and Reproductive Health30. Vitamin B12 and Diabetes31. Biotin Status Screening32. Prostate Cancer and Applications of Vitamin K33. Non-alcoholic Fatty Liver Disease and Use of Folate34. Scenarios of Low Vitamin K IntakesIII Genetic Machinery and its Function35. Transcriptional Control of Cells by Vitamin D36. Transcriptome Analysis for Vitamin B3 (Niacin) and its Receptor GPR109A37. Novel preventive mechanisms of vitamin B6 against inflammation, inflammasome, and chronic diseases38. Vitamins and Epigenetics
