Description
Neuroscience of Alcohol: Mechanisms and Treatment presents the fundamental information necessary for a thorough understanding of the neurobiological underpinnings of alcohol addiction and its effects on the brain. Offering thorough coverage of all aspects of alcohol research, treatment and prevention, and containing contributions from internationally recognized experts, the book provides students, early-career researchers, and investigators at all levels with a fundamental introduction to all aspects of alcohol misuse.Alcohol is one of the world's most common addictive substances, with about two billion individuals worldwide consuming it in one form or another and three million annual deaths that are associated with alcohol misuse. Alcohol alters a variety of neurological processes, from molecular biology, to cognition. Moreover, addiction to alcohol can lead to numerous other health concerns and damage virtually every organ system in the body, making diagnosis and treatment of individuals addicted to alcohol of critical importance.- Integrates cutting-edge research on the pharmacological, cellular and molecular aspects of alcohol use, along with its effects on neurobiological function- Discusses alcohol use as a component of dual-use and poly addictions- Outlines numerous screening and treatment strategies for alcohol misuse- Covers both the physical and psychological effects of alcohol use and withdrawals to provide a fully-formed view of alcohol dependency and its effects
Table of Contents
PART I: INTRODUCTORY CHAPTERS1. Becoming a "Successful" Drinker and a Graduate: A Sociological Perspective on Alcohol Consumption by University Students2. Molecular Genetics Meets Sociology: Birth Cohort Effects on Alcohol Use and Relationship With Candidate Genes3. Alcohol and Women: Unique Risks, Effects, and Implications for Clinical Practice4. ADH and ALDH Polymorphisms in Alcoholism and Alcohol Misuse/Dependence5. Acetaldehyde in the Brain After Ethanol Exposure: Research Progress and Challenges6. Consequences of Ethanol Exposure on Neurodevelopment7. Animal Models of Binge Drinking: Behavior and Clinical RelevancePART II: NEUROBIOLOGY8. Prenatal Alcohol Exposure: Developmental Abnormalities in the Brain9. Connecting Prenatal Alcohol, Its Metabolite Acetaldehyde, and the Fetal Brain10. Fetal Alcohol Exposure and the Central Nervous Control of Breathing11. Synaptic Plasticity in the Hippocampus and Alcohol Exposure During Brain Development12. Ethanol and Cortical Spreading Depression: The Protective Role of α-Tocopherol13. Brain Electrophysiological Signatures in Human Alcoholism and Risk14. Alcohol and Hippocampal Epileptiform Activity15. Effects of Alcohol on the Corpus Callosum16. The Role of the Lateral Habenula Circuitries in Alcohol Use Disorders17. Ventral Pallidum and Alcohol Addiction18. The Hyperpolarization-Activated Cyclic Nucleotide-Gated Ion Channels in the Rewarding Effects of Ethanol19. Neuroimmune Aspects of Alcoholism and Affective Comorbidity20. Social Drinking and Motor Inhibition: Evidences From FMRI Go/Nogo Tasks fMRI Studies on Alcohol Effect on Inhibition21. Myelopathy and Neuropathy Associated With Alcoholism22. Alcohol Consumption and the Risk of Amyotrophic Lateral Sclerosis23. Alcohol and Pain Interactions24. Neurobiological Aspects of Ethanol-Derived Salsolinol25. Brain Networks in Active Alcoholism and Enduring Recovery: Functional Magnetic Resonance Imaging, Electrophysiological Studies, and Implications for Targeted Treatments26. Central Role of Amygdala and Hypothalamus Neural Circuits in Alcohol Withdrawal SymptomPART III: PSYCHOLOGY, BEHAVIOR, AND ADDICTION27. Neural Reward Processing in Human Alcoholism and Risk: A Focus on Event-Related Potentials, Oscillations, and Neuroimaging28. Occipito-Temporal Sensitivity and Emotional Faces in Alcohol Use Disorder29. Alcohol and Violence in Psychopathy and Antisocial Personality Disorder: Neural Mechanisms30. Language Lateralization in Fetal Alcohol Spectrum Disorders31. Deprivation in Rewards and Alcohol Misuse32. Alcohol (Mis)Use in Individuals With Mild to Borderline Intellectual Disability33. Sex, Stress, and Neuropeptides Interact to Influence Alcohol Consumption34. Maternal Separation Stress in Fetal Alcohol Spectrum Disorders: A Case of Double Whammy35. Impulsivity and Binge Drinking: A Neurocognitive Perspective36. Acetaldehyde and Motivation37. Age-Related Differences in the Appetitive and Aversive Motivational Effects of Alcohol38. Alcoholism in Bipolar Disorders: An Overview of Epidemiology, Common Pathogenetic Pathways, Course of Disease, and Implications for Treatment39. Socio-Emotional Deficits in Severe Alcohol Use Disorders40. Relapse Risks in Patients With Alcohol Use Disorders41. The Neurocognitive Effects of Alcohol Hangover: Patterns of Impairment/Nonimpairment Within the Neurocognitive Domains of the Diagnostic and Statistical Manual of Mental Disorders, 5th EditionPART IV: PHARMACOLOGY, NEUROACTIVES, MOLECULAR, AND CELLULAR BIOLOGY42. Neuroactive Steroids and Ethanol Exposure: Relevance to Ethanol Sensitivity and Alcohol Use Disorders Risk43. Alcohol's Effects on Extracellular Striatal Dopamine44. Nicotinic Cholinergic Mechanisms in Alcohol Abuse and Dependence45. Opioid System and Alcohol Consumption46. The Enkephalinergic System and Ethanol Effects47. Alcohol and Central Glutamate Activity: What Goes Up Must Come Down?48.
