ヒト生殖・出生前遺伝学 Human Reproductive and Prenatal Genetics

著者名：Leung, Peter C.K. (EDT)/Qiao, Jie (EDT)

Academic Press（2018/08/28発売）

• 言語：ENG
• ISBN：9780128135709
• eISBN：9780128135716

Description

Human Reproductive and Prenatal Genetics presents the latest material from a detailed molecular, cellular and translational perspective. Considering its timeliness and potential international impact, this all-inclusive and authoritative work is ideal for researchers, students, and clinicians worldwide. Currently, there are no comprehensive books covering the field of human reproductive and prenatal genetics. As such, this book aims to be among the largest and most useful references available.Named a Highly Commended book in the Basic and Clinical Sciences by the British Medical Association.- Features chapter contributions from leading international scientists and clinicians- Provides in-depth coverage of key topics in human reproductive and prenatal genetics, including genetic controls, fertilization and implantation, in vitro culture of the human embryo for the study of post-implantation development, and more- Identifies how researchers and clinicians can implement the latest genetic, epigenetic, and –omics based approaches

Table of Contents

Part I. Reproductive Tract Development and Gametogenesis1. Developmental Genetics of the Male Reproductive System2. Genetics and genomics of early gonad development3. Genetics of Meiotic Chromosome Dynamics and Fertility4. Effects of Aging on Sperm Chromatin5. In Vitro Spermatogenesis from Pluripotent Stem Cells6. Developmental Genetics of the Female Reproductive Tract7. The Molecular Genetics of Oogenesis8. Epigenetic Control of Oocyte Development9. RNA Binding Protein Networks and Translational Regulation in Oocytes10. Translational Regulation of Gene Expression during Oogenesis and Pre-implantation Embryo Development11. MicroRNAs in Gametes and Preimplantation Embryos: Clinical ImplicationsPart II. Embryo Implantation, Placenta Development and Pregnancy12. Transcriptomics of the Human Endometrium and Embryo Implantation13. Epigenetic Modifications in the Human Placenta 14. microRNAs in pregnancy: implications for basic research and clinical management15. Genetics and Genomics of Preterm Birth16. The Intergenerational Effects on Fetal ProgrammingPart III. Infertility and Assisted Reproductive Technology17. Genetic Testing in Male Infertility18. Genetics and Genomics of Endometriosis19. Genetics and Genomics of Primary Ovarian Insufficiency20. Genetics of Polycystic Ovary Syndrome21. Genetics and Genomics of Recurrent Pregnancy Loss22. Human Genetics and Assisted Reproduction in Endometriosis23. Uterine TransplantationPart IV. Preimplantation/Prenatal Genetic Diagnosis and Screening24. Epidemiology and Genetics of Human Aneuploidy25. Next Generation Sequencing for Gene Panels and Clinical Exomes26. Chromosomal Microarrays and Exome Sequencing for Diagnosis of Fetal Abnormalities27. Noninvasive Prenatal Testing for Genetic Diseases28. Non-Invasive Prenatal Testing by Cell-Free DNA: Technology, Biology, Clinical Utility and Limitations29. Prenatal diagnosis and treatment of genetic steroid disorders30. Application of Gene-Editing Technologies in Embryos and Their Potential for Gene Therapy