Description
Gain a foundational understanding of renal physiology and how the renal system functions in health and disease. Renal Physiology: Mosby Physiology Series explains the fundamentals of this complex subject in a clear and concise manner, while helping you bridge the gap between normal kidney function and disease with pathophysiology content throughout the book.- Helps you easily master the material in a systems-based curriculum with learning objectives, "In the Clinic" and "At the Molecular Level" boxes, chapter summaries, clinical cases with review questions and answers, self-study questions, and a comprehensive exam- Includes more than 250 clear, 2-color diagrams that simplify complex concepts- Features clinical commentaries that show you how to apply what you've learned to real-life clinical situations- Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devicesComplete the Mosby Physiology Series! Systems-based and portable, these titles are ideal for integrated programs:- Blaustein, Kao, & Matteson: Cellular Physiology and Neurophysiology- Cloutier: Respiratory Physiology- Pappano & Wier: Cardiovascular Physiology- Johnson: Gastrointestinal Physiology- White, Harrison, & Mehlmann: Endocrine and Reproductive Physiology- Hudnall: Hematology: A Pathophysiologic Approach
Table of Contents
Introduction1. Physiology of Body Fluids1.1. Objectives1.2. Concept of Steady-State Balance1.3. Physicochemical Properties of Electrolyte Solutions1.4. Molarity and Equivalence1.5. Osmosis and Osmotic Pressure1.6. Osmolarity and Osmolality1.7. Tonicity1.8. Oncotic Pressure1.9. Specific Gravity1.10. Volumes of Body Fluid Compartments1.11. Composition of Body Fluid Compartments1.12. Fluid Exchange between Body Fluid Compartments1.13. Capillary Fluid Exchange1.14. Cellular Fluid Exchange1.15. Summary1.16. Key Words and Concepts1.17. Self-Study Problems2. Structure and Function of the Kidneys2.1. Objectives2.2. Structure of the Kidneys2.3. Gross Anatomy2.4. Ultrastructure of the Nephron2.5. Ultrastructure of the Glomerulus2.6. Ultrastructure of the Juxtaglomerular Apparatus2.7. Innervation of the Kidneys2.8. Summary2.9. Key Words and Concepts2.10. Self-Study Problems3. Glomerular Filtration and Renal Blood Flow3.1. Objectives3.2. Renal Clearance3.3. Glomerular Filtration Rate3.4. Glomerular Filtration3.5. Determinants of Ultrafiltrate Composition3.6. Dynamics of Ultrafiltration3.7. Renal Blood Flow3.8. Regulation of Renal Blood Flow and Glomerular Filtration Rate3.9. Sympathetic Nerves3.10. Angiotensin II3.11. Prostaglandins3.12. Nitric Oxide3.13. Endothelin3.14. Bradykinin3.15. Adenosine3.16. Natriuretic Peptides3.17. Adenosine Triphosphate3.18. Glucocorticoids3.19. Histamine3.20. Dopamine3.21. Summary3.22. Key Words and Concepts3.23. Self-Study Problems4. Renal Transport Mechanisms: NaCl and Water Absorption Along the Nephron4.1. Objectives4.2. General Principles of Membrane Transport4.3. General Principles of Transepithelial Solute and Water Transport4.4. NaCl, Solute, and Water Reabsorption Along the Nephron4.5. Proximal Tubule4.6. Henle's Loop4.7. Distal Tubule and Collecting Duct4.8. Regulation of NaCl and Water Reabsorption4.9. Summary4.10. Key Words and Concepts4.11. Self-Study Problems5. Regulation of Body Fluid Osmolality: Regulation of Water Balance5.1. Objectives5.2. Arginine Vasopressin5.3. Osmotic Control of Arginine Vasopressin Secretion5.4. Hemodynamic Control of Arginine Vasopressin Secretion5.5. Arginine Vasopressin Actions on the Kidneys5.6. Thirst5.7. Renal Mechanisms for Dilution and Concentration of the Urine5.8. Medullary Interstitium5.9. Vasa Recta Function5.10. Assessment of Renal Diluting and Concentrating Ability5.11. Summary5.12. Key Words and Concepts5.13. Self-Study Problems6. Regulation of Extracellular Fluid Volume and NaCl Balance6.1. Objectives6.2. Whole-Body Na+ Balance6.3. Concept of Effective Circulating Volume6.4. Volume-Sensing Systems6.5. Volume Sensors in the Low-Pressure Cardiopulmonary Circuit6.6. Volume Sensors in the High-Pressure Arterial Circuit6.7. Volume Sensor Signals6.8. Renal Sympathetic Nerves6.9. Renin-Angiotensin-Aldosterone System6.10. Natriuretic Peptides6.11. Arginine Vasopressin6.12. Control of Renal NaCl Excretion During Euvolemia6.13. Mechanisms for Maintaining Constant Na+ Delivery to the Distal Tubule in Euvolemia6.14. Regulation of Distal Tubule and Collecting Duct Na+ Reabsorption in Euvolemia6.15. Control of Na+ Excretion with Volume Expansion6.16. Control of Na+ Excretion with Volume Contraction6.17. Edema6.18. Alterations in Starling Forces6.19. Capillary Hydrostatic Pressure (Pc)6.20. Plasma Oncotic Pressure (πc)6.21. Lymphatic Obstruction6.22. Capillary Permeability6.23. Role of the Kidneys6.24. Summary6.25. Key Words and Concepts6.26. Self-Study Problems7. Regulation of Potassium Balance7.1. Objectives7.2. Overview of K+ Homeostasis7.3. Regulation of Plasma [K+]7.4. Epinephrine7.5. Insulin7.6. Aldosterone7.7. Alterations of Plasma [K+]7.8. Acid-Base Balance7.9. Plasma Osmolality7.10. Cell Lysis7.11. Exercise7.12. K+ Excretion by the Kidneys7.13. Cellular Mechanisms of K+ Transport by Principal Cells and Intercalated Cells in the Distal Tubule and Collecting Duct7.14. Regulation of K+ Secretion by the Distal Tubule and Collecting Duct7.15. Plasma [K+]7.16.
