Managing the Drug Discovery Process : How to Make It More Efficient and Cost-Effective

著者名：Miller, Susan/Moos, Walter/Munk, Barbara/Munk, Stephen

Woodhead Publishing（2016/11/08発売）

• 言語：ENG
• ISBN：9780081006252
• eISBN：9780081006320

Description

Managing the Drug Discovery Process: How to Make It More Efficient and Cost-Effective thoroughly examines the current state of pharmaceutical research and development by providing chemistry-based perspectives on biomedical research, drug hunting and innovation. The book also considers the interplay of stakeholders, consumers, and the drug firm with attendant factors, including those that are technical, legal, economic, demographic, political, social, ecological, and infrastructural. Since drug research can be a high-risk, high-payoff industry, it is important to researchers to effectively and strategically manage the drug discovery process.This book takes a closer look at increasing pre-approval costs for new drugs and examines not only why these increases occur, but also how they can be overcome to ensure a robust pharmacoeconomic future. Written in an engaging manner and including memorable insights, this book is aimed at redirecting the drug discovery process to make it more efficient and cost-effective in order to achieve the goal of saving countless more lives through science. A valuable and compelling resource, this is a must-read for all students and researchers in academia and the pharmaceutical industry.- Considers drug discovery in multiple R&D venues, including big pharma, large biotech, start-up ventures, academia, and nonprofit research institutes- Analyzes the organization of pharmaceutical R&D, taking into account human resources considerations like recruitment and configuration, management of discovery and development processes, and the coordination of internal research within, and beyond, the organization, including outsourced work- Presents a consistent, well-connected, and logical dialogue that readers will find both comprehensive and approachable

Table of Contents

Section A: Introduction and Overview1: Backgrounder: Medicinal chemistry: Research, discovery, art, scienceSection B: Preprofessional Education2: Introduction: Preprofessional education3: Two-year certification and degree programs4: Four-year undergraduate degree programs5: The big decisionSection C: Graduate and Professional Education6: Graduate and postgraduate education at a crossroads7: Master's degree programs8: Doctoral and professional programs9: The big leapSection D: Research and Discovery10: Drug discovery: Chaos can be your friend or your enemy11: Drug discovery: Standing on the shoulders of giants12: Research and discovery: The difficult we do immediately—The impossible takes only a little longerSection E: Chemical Development, Quality Requirements, and Regulatory Affairs13: Turning a potent agent into a registered product14: Chemical development: Synthetic studies and engineering aspects15: Chemical development: Analytical studies16: FDA path and process: Sponsor's regulatory tasks for drug approvalSection F: Pharmaceutical Research and Development: Concluding Remarks17: Epilogue