Description
Methods in Neurosciences, Volume 11: Receptors: Model Systems and Specific Receptors is a compilation of papers that describes techniques and information that are important to the neurosciences. This volume discusses preferred receptor techniques, molecular techniques, and methods to determine receptor subclasses and localization in the ligand design. The first paper discusses the steroid receptor found in the central nervous system for steroid hormones that affects strongly the structure and function of both developed and immature nervous systems. Another paper describes how a glycoprotein of 79.5 kDa (transferrin) carries iron in the blood stream for delivery to different tissues, after the transferrin has bound with a specific receptor on the surface of the cell. This book also explains the binding sites of pituitary adenylate cyclase-activating polypeptide in the human brain, while one paper analyzes the neurotensin receptors during the primary culture of neurons. This volume then also analyzes the structure and function of the fast nerve growth factor receptor, particularly how a signal on the outside of a cell is transmitted to the cell's interior. This collection is helpful for microbiologists, cellular researchers, students, and professors in the discipline of neurosciences.
Table of Contents
Contributors to Volume 11PrefaceVolumes in Series 1. Steroid Receptors in the Central Nervous System 2. Membrane Receptor for Glucocorticoids in Mammalian Neurons 3. Interleukin 1 Receptors in the Brain-Endocrine-Immune Axis 4. Vasoactive Peptides and Their Receptors 5. Melanotropin Receptors of the Brain 6. Melatonin Binding Sites 7. Transferrin Receptors in the Central Nervous System 8. Binding Sites of Pituitary Adenylate Cyclase-Activating Polypeptide in Human Brain 9. Role of Cholecystokinin Type B Receptor in Nociception Studied with Peptide Agonists and Antagonists 10. Cholecystokinin Receptors: Radioligand Binding and Afñnity Labeling 11. Endothelin Receptors in Neural Systems 12. Natriuretic Peptide Receptors 13. Structural and Functional Identification of Insulin-like Growth Factor Receptors 14. Methods for Studying Central Serotonergic Receptors 15. Analysis of Serotonin 5-HT1A Receptors in Primary Neuronal Culture 16. Characterization of the Bombesin/Gastrin-Releasing Peptide Receptor in Swiss 3T3 Fibroblasts 17. Receptors for Bombesinlike Peptides in the Rat Central Nervous System 18. Retinal Insulin Receptors 19. Pancreatic Polypeptide Receptors in Rat Brain 20. Neurotensin Receptors in Primary Culture of Neurons 21. Analysis of the Structure and Function of the Fast Nerve Growth Factor Receptor 22. Solubilization and Physicochemical Characterization of 5-HT3 Receptor-Binding Sites 23. Solubihzadon and Characterization of the Receptor for Gastrin-Releasing Peptide 24. Assays for Pituitary Adenylate Cyclase-Acdvadng Peptide Receptors Coupled to Adenylate Cyclase: Comparison between Rat Brain and Human Neuroblastoma CellsIndex
