Fetal Endocrinology and Metabolism : Current Topics in Experimental Endocrinology, Vol. 5

著者名：Martini, L (EDT)/James, V. H. T. (EDT)

Academic Press（2013/10/22発売）

• 言語：ENG
• ISBN：9780121532055
• eISBN：9781483217376

Description

Current Topics in Experimental Endocrinology, Volume 5: Fetal Endocrinology and Metabolism covers various aspects of fetal endocrinology. The book discusses studies of the hypothalamic-pituitary unit which emphasize the unique aspects of the fetal endocrine system; in vitro fertilization; and factors controlling placental endocrine function in domestic animals. The text also describes the role and kinetics of thyroid in fetal development; the placental transfer of carbohydrates; and fetal hormones and carbohydrate utilization. The regulation of partition of protein during pregnancy; the mineral needs of the fetus; and the fetal metabolism of cortisol are also considered. The book further tackles normal and abnormal sexual differentiation and the metabolic errors of adrenal steroidogenesis. Physiologists, endocrinologists, obstetricians, gynecologists, and students taking related courses will find the book invaluable.

Table of Contents

ContributorsPrefaceThe Fetal Neuroendocrine Axis I. Introduction II. The Development of the Hypothalamus and Adenohypophysis III. The Secretion and Function of Fetal Adenohypophyseal Hormones IV. Autonomy of the Fetal Neuroendocrine Unit ReferencesIn Vitro Fertilization I. The Natural Ovulatory Cycle and IVF II. The Stimulated or Controlled Ovulatory Cycle III. Maturation of the Oocyte IV. The Technique of in Vitro Fertilization V. The Use of IVF in Male and Idiopathic Infertility ReferencesFactors Controlling Placental Endocrine Function in Domestic Animals I. Introduction II. Control of Placental Steroid Secretion by Fetal Cortisol in Domestic Animals III. Control of Secretion of Placental Lactogens IV. Effects of β-Catecholaminergic Drugs on the Placenta V. Conclusions ReferencesThe Fetal Thyroid I. Introduction II. The Choice of Preparation III. The Morphological and Secretory Development of the Gland IV. The Placental Barrier V. The Role of the Thyroid in Fetal Development VI. Fetal Thyroid Hormone Kinetics VII. Perinatal Thyroid Hormone Concentrations VIII. Conclusion ReferencesCarbohydrate Metabolism I. Introduction II. Maternal Hormonal and Metabolic Adaptations III. Early Embryonic Development IV. Placental Transfer of Carbohydrates V. Fetal Hormones and Carbohydrate Utilization VI. Fetal Metabolic Pathways VII. Summary ReferencesRegulation of Partition of Protein during Pregnancy I. Introduction II. Placental Protein III. Fetal Protein IV. Free Amino Acid Pools V. Maternal Protein ReferencesMineral Needs of the Fetus I. Introduction II. Calcium, Phosphate, Magnesium III. Parathyroid Hormone (PTH) IV. Vitamin D V. Calcitonin VI. Hormone Interrelations VII. Conclusion ReferencesFetal Metabolism of Cortisol I. Introduction II. Circulating Levels of Cortisol in the Fetus III. Sources of Cortisol in the Fetal Circulation IV. Fate of Fetal Cortisol V. Significance of Cortisol in the Fetus VI. Summary ReferencesSexual Differentiation: Normal and Abnormal I. Embryology of Sexual Differentiation II. Determinants of Phenotypic Differentiation III. Genetic Control of Sexual Differentiation IV. Sexual Differentiation of the Brain V. Male Pseudohermaphroditism VI. XX Males and True Hermaphroditism VII. Female Pseudohermaphroditism ReferencesMetabolic Errors of Adrenal Steroidogenesis I. Introduction II. Steroidogenesis and Enzymatic Conversions of Adrenal Steroid Hormones III. Fetal Sexual Development IV. Enzyme Defects in Congenital Adrenal Hyperplasia V. The Zona Fasciculata and Zona Glomerulosa as Separate Glands VI. Treatment of Congenital Adrenal Hyperplasia VII. Genetics of Congenital Adrenal Hyperplasia VIII. Prenatal Diagnosis of Congenital Adrenal Hyperplasia IX. Summary ReferencesIndex