Tendon Regeneration : Understanding Tissue Physiology and Development to Engineer Functional Substitutes

著者名：Gomes PhD, Manuela E. (EDT)/Reis PhD, DSc, Hon. Causa MD, Hon Causa PhD, FBSE, FTERM, Ru/Rodrigues PhD, Márcia T. (EDT)

Academic Press（2015/08/08発売）

• 言語：ENG
• ISBN：9780128015902
• eISBN：9780128016008

Description

Tendon Regeneration: Understanding Tissue Physiology and Development to Engineer Functional Substitutes is the first book to highlight the multi-disciplinary nature of this specialized field and the importance of collaboration between medical and engineering laboratories in the development of tissue-oriented products for tissue engineering and regenerative medicine (TERM) strategies.Beginning with a foundation in developmental biology, the book explores physiology, pathology, and surgical reconstruction, providing guidance on biological approaches that enhances tendon regeneration practices.Contributions from scientists, clinicians, and engineers who are the leading figures in their respective fields present recent findings in tendon stem cells, cell therapies, and scaffold treatments, as well as examples of pre-clinical models for translational therapies and a view of the future of the field.- Provides an overview of tendon biology, disease, and tissue engineering approaches- Presents modern, alternative approaches to developing functional tissue solutions discussed- Includes valuable information for those interested in tissue engineering, tissue regeneration, tissue physiology, and regenerative medicine- Explores physiology, pathology, and surgical reconstruction, building a natural progression that enhances tendon regeneration practices- Covers recent findings in tendon stem cells, cell therapies, and scaffold treatments, as well as examples of pre-clinical models for translational therapies and a view of the future of the field

Table of Contents

PrefaceManuela E. Gomes, Marcia T. Rodrigues, Rui L. Reis1. Tendon Physiology and Mechanical Behavior: Structure-Function Relationships2. Tendon Resident Cells – Function and Features 3. Mechanobiology of TendonsSection II – Pathologies and repair of tendons4. Tendinopathies (I): Understanding Epidemiology, Pathology,  Healing and Treatment5. Tendinopathies (II): Etiology, Pathology, and Healing of Tendon Injury and DiseaseSection III- Tendon Regenerative Medicine approaches6. Cell Based Approaches for Tendon Regeneration7. GF Approaches in Tendon StimulationSection IV – Scaffolds-Based Approaches8. Scaffold-Based Approaches (I): Engineering anisotropic 2D and 3D structures for tendon repair and regeneration9. Scaffold-Based Approaches (II): Biological and synthetic based scaffolds for tendon regenerationSection V – Tendon Tissue Engineering10. Tendon TE: Hierarchical and Biomimetic Structures to Support the Regeneration of Tendon Tissues11. Tendon TE: Multifactoral Tendon Tissue Engineering Strategies12. Tendon TE: Combined Tissue Engineering Approach for the Regeneration of Tendons13. Tendon TE: Biomaterial scaffolds for tendon tissue engineering14. Pre-Clinical models for Tendon Translational Therapies15. Scaffold design for integrative tendon-bone repair